Turnbull D, Fisher P C, Mills G H, Morgan-Hughes N J
University of Sheffield, Academic Anaesthetic Unit, Sheffield, South Yorkshire, UK.
Br J Anaesth. 2005 May;94(5):675-82. doi: 10.1093/bja/aei091. Epub 2005 Feb 25.
Heat and moisture exchangers in combination with a bacterial and viral filter (HMEF) are widely used during general anaesthesia. Excess patient secretions occluding the HMEF have been responsible for previous case reports of airway obstruction. A previous study suggested that differences in HMEF design might contribute to filter obstruction under wet conditions.
We tested 14 types of HMEF under wet conditions to establish which design features contributed to HMEF obstruction. Incremental amounts of saline were added to each filter. The pressure across the filter was measured with an air flow of 60 litre min(-1).
We observed that saline added to the filter was often not easily visible to the casual observer. This concealment volume varied between filters. Ceramic hydrophobic pleated-membrane filters did not absorb saline and their resistance did not change. The composite filter where the moisture exchange component was either polyurethane foam or cellulose absorbed saline and contributed to a rise in resistance of 70-480% with the higher value more typical of the cellulose-paper-based HMEF.
The ideal HMEF for use during general anaesthesia should prevent the passage of viral, bacterial and prion material, should provide this filtration performance even under wet conditions, should supplement humidification of the inspired air and anaesthetic gases and should not increase respiratory work. We have identified large variations in HMEF performance under wet conditions. Users should be aware of performance variation in HMEFs and use a filter suited to the intended application.
结合细菌和病毒过滤器的热湿交换器(HMEF)在全身麻醉期间广泛使用。此前有病例报告称,患者过多的分泌物阻塞HMEF会导致气道梗阻。此前一项研究表明,HMEF设计的差异可能导致在潮湿条件下过滤器阻塞。
我们在潮湿条件下测试了14种HMEF,以确定哪些设计特征会导致HMEF阻塞。向每个过滤器中逐渐添加生理盐水。在空气流速为60升/分钟的情况下测量过滤器两端的压力。
我们观察到,随意观察者通常不容易看到添加到过滤器中的生理盐水。这种隐藏量因过滤器而异。陶瓷疏水褶膜过滤器不吸收生理盐水,其阻力不变。水分交换组件为聚氨酯泡沫或纤维素的复合过滤器吸收生理盐水,导致阻力增加70% - 480%,较高的值更典型地出现在基于纤维素纸的HMEF中。
全身麻醉期间使用的理想HMEF应能防止病毒、细菌和朊病毒物质通过,即使在潮湿条件下也应具备这种过滤性能,应补充吸入空气和麻醉气体的加湿,且不应增加呼吸功。我们已经确定了HMEF在潮湿条件下性能的巨大差异。使用者应了解HMEF的性能差异,并使用适合预期应用的过滤器。