Beydon L, Tong D, Jackson N, Dreyfuss D
Réanimation Chirurgicale, Hôpital Henri Mondor, Créteil, France.
Chest. 1997 Sep;112(3):739-44. doi: 10.1378/chest.112.3.739.
This study on ventilated patients in ICUs examined a large sample of heat and moisture exchanger filters (HMEFs) to determine whether simple clinical parameters are correlated with exchanger humidity output.
A total of 594 HMEFs (18 types of HMEF) were tested in nine university hospital ICUs.
Each HMEF was tested on one different unselected and consecutive patient for 24 h.
The following parameters were rated at each tracheal aspiration on a scale of 0 to 3: secretion abundance, viscosity (Visc), suction catheter adherence (Adh) to the endotracheal tube, and the amount of water condensed in the flex tube (Cond). Individual values for each type of HMEF and each variable were averaged and correlated with the humidity output (HO) of the HMEFs, values which were supplied by the manufacturers.
There were significant correlations between HO and Cond (r=0.82, p<10(-3)), Visc (r=-0.67, p=0.002), and Adh (r=-0.56, p=0.01). A second study recorded the same variables, for three consecutive 24-h periods, using first a high-humidifying HMEF (DAR Hygrobac), followed by a low-humidifying one (Pall BB22-15), and again DAR Hygrobac. Visc and Adh were higher (p<0.05) and Cond was lower (p<0.05) with the Pall than with the DAR.
Simple clinical parameters correlate well with the efficiency of HMEFs. The apparent water condensed in the flex tubing seems to be the best indicator of the humidifying efficiency of HMEFs.
本研究对重症监护病房(ICU)中使用呼吸机的患者进行了大量热湿交换器过滤器(HMEF)样本检测,以确定简单的临床参数是否与交换器湿度输出相关。
在9家大学医院的ICU中对总共594个HMEF(18种类型的HMEF)进行了测试。
每个HMEF在一名未经挑选的连续患者身上测试24小时。
每次气管抽吸时,对以下参数按0至3级进行评分:分泌物量、黏稠度(Visc)、吸痰管与气管导管的粘连情况(Adh)以及挠性管中凝结的水量(Cond)。对每种类型的HMEF和每个变量的个体值进行平均,并与HMEF的湿度输出(HO)相关联,湿度输出值由制造商提供。
HO与Cond(r = 0.82,p < 10⁻³)、Visc(r = -0.67,p = 0.002)和Adh(r = -0.56,p = 0.01)之间存在显著相关性。第二项研究在三个连续的24小时时间段内记录了相同的变量,首先使用高湿度的HMEF(DAR Hygrobac),然后使用低湿度的HMEF(Pall BB22 - 15),之后再次使用DAR Hygrobac。与DAR相比,使用Pall时Visc和Adh更高(p < 0.05),Cond更低(p < 0.05)。
简单的临床参数与HMEF的效率密切相关。挠性管中明显凝结的水似乎是HMEF加湿效率的最佳指标。