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铁强化对营养性贫血的影响。

The impact of iron fortification on nutritional anaemia.

作者信息

Lynch Sean R

机构信息

Department of Internal Medicine, Eastern Virginia Medical School, Norfolk, VA, USA.

出版信息

Best Pract Res Clin Haematol. 2005 Jun;18(2):333-46. doi: 10.1016/j.beha.2004.09.003.

Abstract

Iron deficiency continues to be the most prevalent nutritional deficiency disorder in the world, affecting an estimated two billion people, most of whom live in developing countries. It has far-reaching effects on the health, well-being and productivity of those affected. Iron fortification of food is regarded as the most cost-effective method for reducing the prevalence of nutritional iron deficiency. In industrialized countries this has had an important beneficial effect; however, nutritional anaemia remains very prevalent in developing countries, and iron fortification appears until recently to have had little impact. Two important reasons for the latter situation are inadequate documentation of the magnitude of the iron deficiency component of anaemia in different regions of the world, and the use of iron compounds that are poorly bioavailable in fortification programmes. Several recent interventions using innovative approaches to dietary fortification that ensure the delivery of adequate quantities of bioavailable iron have demonstrated that iron fortification of food can be an effective and implementable strategy for controlling nutritional iron deficiency in non-industrialized countries.

摘要

缺铁仍然是世界上最普遍的营养缺乏症,估计影响着20亿人,其中大多数生活在发展中国家。它对受影响者的健康、福祉和生产力有着深远影响。食品铁强化被认为是降低营养性缺铁患病率最具成本效益的方法。在工业化国家,这已产生了重要的有益影响;然而,营养性贫血在发展中国家仍然非常普遍,而且直到最近,铁强化似乎几乎没有产生影响。后一种情况的两个重要原因是,世界不同地区贫血中铁缺乏成分的严重程度记录不足,以及在强化计划中使用生物利用率低的铁化合物。最近一些采用创新饮食强化方法的干预措施确保了提供足够数量的生物可利用铁,这些措施表明,食品铁强化可以成为控制非工业化国家营养性缺铁的有效且可实施的策略。

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