Kühnel Thomas S, Schurr Christian, Wagner Birgit, Geisler Peter
Department of Otorhinolaryngology, University of Regensburg, Regensburg, Germany.
Laryngoscope. 2005 Mar;115(3):475-80. doi: 10.1097/01.mlg.0000157842.40412.5f.
OBJECTIVES/HYPOTHESIS: The objectives were 1) to demonstrate the efficacy of tongue base suspension with the Repose System in modifying the posterior airway space on the basis of morphological changes in the retrolingual space and 2) to determine the implications of this procedure for the treatment of obstructive sleep apnea syndrome on polysomnographic and psychometric data.
A prospective, nonrandomized study.
Polysomnography was performed before as well as 3 and 12 months after surgery in patients undergoing tongue base suspension using the Repose System. To identify morphological changes in the posterior airway space, lateral cephalometric radiography and videoendoscopy of the pharynx were performed preoperatively and postoperatively. Twenty-eight male patients with obstructive sleep apnea syndrome were included in the study. A suspension suture anchored intraorally at the mandible was passed submucosally in the body of the tongue, with suture tightness adjusted individually.
The posterior airway space was widened by at least 2 mm in 60% of cases. Daytime sleepiness improved subjectively in 67% of patients, and the respiratory disturbance index improved postoperatively in 55%. The correlation between posterior airway space widening and the improvements in daytime sleepiness and respiratory disturbance index was not significant.
Surgical intervention in obstructive sleep apnea syndrome with the Repose System does not result in permanent anatomical change in the posterior airway space.
目的/假设:目标为1)基于舌后间隙的形态学变化,证明使用Repose系统进行舌根悬吊术在改变后气道空间方面的疗效,以及2)根据多导睡眠图和心理测量数据确定该手术对阻塞性睡眠呼吸暂停综合征治疗的意义。
一项前瞻性、非随机研究。
对使用Repose系统进行舌根悬吊术的患者,在手术前以及术后3个月和12个月进行多导睡眠图检查。为了确定后气道空间的形态学变化,术前和术后均进行了咽部侧位头影测量和视频内镜检查。28名患有阻塞性睡眠呼吸暂停综合征的男性患者纳入研究。一根在下颌骨口腔内固定的悬吊缝线经黏膜下穿过舌体,缝线松紧度因人而异进行调整。
60%的病例后气道空间至少增宽2毫米。67%的患者主观上白天嗜睡情况改善,55%的患者术后呼吸紊乱指数改善。后气道空间增宽与白天嗜睡情况及呼吸紊乱指数改善之间的相关性不显著。
使用Repose系统对阻塞性睡眠呼吸暂停综合征进行手术干预不会导致后气道空间出现永久性解剖学改变。