Fedorowicz Z, Lawrence D, Gutierrez P
Cochrane Database Syst Rev. 2005 Jan 25(1):CD004242. doi: 10.1002/14651858.CD004242.pub3.
Age-related cataract accounts for more than 40% of cases of blindness in the world with the majority of people who are blind from cataract found in the developing world. With the increased number of people with cataract there is an urgent need for cataract surgery to be made available as a day care procedure.
To provide reliable evidence regarding the safety, feasibility, effectiveness and cost-effectiveness of cataract extraction performed as day care versus in-patient procedure.
We searched the Cochrane Central Register of Controlled Trials - CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) on The Cochrane Library (Issue 3 2004), MEDLINE (1966 to July 2004), EMBASE (1980 to August 2004) and LILACS (July 2004).
This review includes randomised controlled trials comparing day care and in-patient surgery for age-related cataract. The primary outcome was the achievement of a satisfactory visual acuity six weeks after the operation.
Although two trials are included in the review, adequate data were available for only one trial and therefore pooling of data from studies was not attempted. A descriptive summary is presented.
Two trials, involving a total of 1284 people, are included in this review. One trial reported statistically significant differences in early postoperative complication rates in the day care group, with an increased risk of increased intraocular pressure, which had no clinical relevance to visual outcomes four months postoperatively. The mean change in visual acuity (Snellen lines) of the operated eye four months postoperatively was 4.1 (standard deviation (SD) 2.3) for the day care group and 4.1 (SD 2.2) for the in-patient group and not statistically significant. The four-month postoperative mean change in quality of life score measured using the VF14 showed minimal differences between the two groups. Costs were 20% more for the in-patient group and this was attributed to higher costs for overnight stay. One study only reported hotel costs for the non-hospitalised participants making aggregation of data on costs impossible.
AUTHORS' CONCLUSIONS: This review provides some evidence that there is a cost saving but no significant difference in outcome or risk of postoperative complications between day care and in-patient cataract surgery. This is based on one detailed and methodologically sound trial conducted in the developed world. The success, safety and cost-effectiveness of cataract surgery as a day care procedure appear to be acceptable but additional well-designed trials are required to confirm these perceptions.
年龄相关性白内障占全球失明病例的40%以上,大多数因白内障失明的人都在发展中国家。随着白内障患者数量的增加,迫切需要将白内障手术作为日间手术提供。
提供可靠证据,证明白内障日间手术与住院手术相比在安全性、可行性、有效性和成本效益方面的情况。
我们检索了Cochrane系统评价数据库中的Cochrane对照试验中心注册库(CENTRAL,其中包含Cochrane眼科和视力组试验注册库)(2004年第3期)、MEDLINE(1966年至2004年7月)、EMBASE(1980年至2004年8月)和LILACS(2004年7月)。
本综述纳入比较年龄相关性白内障日间手术和住院手术的随机对照试验。主要结局是术后六周达到满意的视力。
尽管综述纳入了两项试验,但只有一项试验有足够的数据,因此未尝试合并研究数据。给出了描述性总结。
本综述纳入两项试验,共涉及1284人。一项试验报告日间手术组术后早期并发症发生率有统计学显著差异,眼压升高风险增加,但这与术后四个月的视力结果无临床相关性。日间手术组术后四个月患眼视力(Snellen视力表行数)的平均变化为4.1(标准差[SD]2.3),住院手术组为4.1(SD 2.2),无统计学显著差异。使用VF14测量的术后四个月生活质量评分的平均变化在两组之间差异极小。住院手术组的费用高出20%,这归因于过夜住院费用较高。只有一项研究报告了非住院参与者的酒店费用,因此无法汇总成本数据。
本综述提供了一些证据,表明白内障日间手术与住院手术相比可节省成本,但在结局或术后并发症风险方面无显著差异。这是基于在发达国家进行的一项详细且方法学合理的试验。白内障日间手术的成功率、安全性和成本效益似乎是可以接受的,但需要更多设计良好的试验来证实这些观点。