De Letter Miet, Santens Patrick, Van Borsel John
Department of Oto-Rhino-Laryngology, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium.
J Commun Disord. 2005 May-Jun;38(3):187-96. doi: 10.1016/j.jcomdis.2004.09.001. Epub 2004 Nov 10.
Dysarthria is a common manifestation in patients with idiopathic Parkinson's disease. This study investigated the effects of levodopa on intelligibility in patients with Parkinson's disease. Ten participants were tested during on- and off-states using the Yorkston and Beukelman intelligibility test (1980). Intelligibility as scored by a panel of speech therapists was significantly improved in the on-condition. No correlation was found, however, between intelligibility and overall severity of the disease or severity of the motor problems. EDUCATIONAL OUTCOMES: As a result of this activity the participant will be able to discuss the effects of levodopa on intelligibility in patients with Parkinson's disease.
构音障碍是特发性帕金森病患者的常见表现。本研究调查了左旋多巴对帕金森病患者言语清晰度的影响。使用约克斯顿和贝克曼言语清晰度测试（1980年）对10名参与者在服药和未服药状态下进行了测试。由一组言语治疗师评分的言语清晰度在服药状态下有显著提高。然而，未发现言语清晰度与疾病的总体严重程度或运动问题的严重程度之间存在相关性。教育成果：通过本次活动，参与者将能够讨论左旋多巴对帕金森病患者言语清晰度的影响。
