Kaiser W, Zazgornik J
II. Medizinische Abteilung, Allgemeines Krankenhaus Linz, Osterreich.
Z Rheumatol. 1992 Jan-Feb;51(1):31-4.
Silicone is able to induce different immunological reactions: Local foreign body reactions with activation of fibroblasts, granuloma formation and clinical manifestation of autoimmune diseases may occur. We report 4 cases with possible autoimmune disease in connection with breast augmentation. In one case explantation lead to both clinical and serological improvement with a decrease of antinuclear antibodies from 1:1280 to 1:160. In addition we report the spectrum of silicone induced systemic side effects and discuss the possible cellular reactions as well as the immunological changes.
可能会出现伴有成纤维细胞活化的局部异物反应、肉芽肿形成以及自身免疫性疾病的临床表现。我们报告了4例与隆乳相关的可能患有自身免疫性疾病的病例。其中1例取出植入物后，临床症状和血清学指标均有改善，抗核抗体从1:1280降至1:160。此外，我们报告了硅酮引发的全身性副作用的范围，并讨论了可能的细胞反应以及免疫变化。
