Schachter J, Hook E W, Martin D H, Willis D, Fine P, Fuller D, Jordan J, Janda W M, Chernesky M
Chlamydia Research Laboratory, Department of Laboratory Medicine, University of California-San Francisco, 1001 Potrero Ave., SFGH 3416, San Francisco, CA 94110, USA.
J Clin Microbiol. 2005 Mar;43(3):1372-3. doi: 10.1128/JCM.43.3.1372-1373.2005.
The Centers for Disease Control and Prevention recommended confirming positive screening tests for Chlamydia trachomatis when positive predictive values are <90%. It is accepted that less sensitive tests (i.e., culture and immunoassays) should not be used to confirm the results of more sensitive nucleic acid amplification tests (NAATs). We show that the same principle applies when NAATs are used for confirmation.
美国疾病控制与预防中心建议,当沙眼衣原体筛查试验的阳性预测值低于90%时,应对阳性结果进行确认。人们公认,不应使用敏感性较低的检测方法(即培养法和免疫测定法)来确认敏感性较高的核酸扩增试验(NAAT)的结果。我们发现,当使用NAAT进行确认时,同样的原则也适用。