Theorell T
National Institute of Psychosocial Factors and Health, Stockholm, Sweden.
Integr Physiol Behav Sci. 1992 Jan-Mar;27(1):32-8. doi: 10.1007/BF02691090.
According to previous animal research and psychological laboratory experiments in humans, plasma prolactin varies in relation to psychosocial stress. However, the findings in published studies are difficult to interpret. In some studies increased levels and, in other studies, decreased levels were observed. The present report summarizes findings from four different real-life stress studies that have had a longitudinal design. Findings indicate that change situations associated with passive coping are accompanied by increased plasma prolactin levels whereas change situations associated with active coping are associated with unchanged or even lowered levels. The regulation of plasma prolactin is part of a dopaminergic system. It is speculated that prolactin may be needed for preservation of vital functions during withdrawal.
根据先前的动物研究以及针对人类的心理实验室实验,血浆催乳素会随着心理社会压力而变化。然而,已发表研究中的结果难以解读。在一些研究中观察到水平升高,而在其他研究中则观察到水平降低。本报告总结了四项采用纵向设计的不同现实生活压力研究的结果。结果表明,与被动应对相关的变化情境会伴随着血浆催乳素水平升高,而与主动应对相关的变化情境则与水平不变甚至降低有关。血浆催乳素的调节是多巴胺能系统的一部分。据推测,在戒断期间维持重要功能可能需要催乳素。