Oddone E Z, Feussner J R, Cohen H J
Division of General Internal Medicine, Duke University Medical Center, Durham, North Carolina.
Clin Geriatr Med. 1992 Feb;8(1):51-67.
Cancer screening of the elderly is warranted for those cancers for which early detection and treatment improve life expectancy. There is excellent evidence to include screening for breast cancer with clinical examination and mammography for elderly women. There is also reasonable evidence to screen for cervical cancer with PAP testing in elderly women who were previously unscreened, although there is no evidence to support continuing the practice in women who have had consecutive normal PAP tests. No evidence supports or refutes screening programs for colon, prostate, skin, or oral cancer in the elderly. The authors recommend including screening for colon and prostate cancer in the routine examination of office patients. The potential benefit for the rare patient in whom an early stage cancer is discovered and treated is large and worth both the physician's and patient's time and effort. The authors recommend screening only patients deemed to be at high risk for skin and oral cancer. The main factor favoring continued screening in the elderly is the burden of suffering and the pronounced increased incidence of the disease in old age. Lastly, the authors recommend against routine screening for lung cancer in the elderly.
对于那些早期发现和治疗可提高预期寿命的癌症,对老年人进行癌症筛查是有必要的。有充分证据表明,老年女性应通过临床检查和乳房X线摄影进行乳腺癌筛查。对于以前未接受过筛查的老年女性,通过巴氏试验筛查宫颈癌也有合理依据,不过对于连续巴氏试验结果正常的女性,没有证据支持继续进行此项筛查。没有证据支持或反驳对老年人进行结肠癌、前列腺癌、皮肤癌或口腔癌的筛查项目。作者建议在门诊患者的常规检查中纳入结肠癌和前列腺癌筛查。对于极少数早期癌症被发现并得到治疗的患者,潜在益处很大,值得医生和患者投入时间和精力。作者建议仅对被认为患皮肤癌和口腔癌高危的患者进行筛查。支持在老年人中继续进行筛查的主要因素是患病痛苦以及老年时疾病发病率显著上升。最后,作者不建议对老年人进行常规肺癌筛查。