Brucki Sonia Maria Dozzi, Takada Leonel Tadao, Nitrini Ricardo
Department of Psychobiology of Federal University of São Paulo, Brazil.
Cognitive and Behavioural Neurology Unity - Hospital das Clínicas - University of São Paulo, SP, Brazil.
Dement Neuropsychol. 2009 Jan-Mar;3(1):61-67. doi: 10.1590/S1980-57642009DN30100012.
Since its first description in 1760, Charles Bonnet syndrome (CBS) has been reported in many studies. The main characteristics are visual hallucinations, preserved awareness of unreal visions, and absence of psychotic symptoms. CBS can occur with lesions located anywhere along the central visual pathway, from the eye to the calcarine fissure.
To describe patients with CBS and carry out a review of the literature.
Six patients with visual hallucinations were evaluated in an outpatient memory clinic between 2001 and 2008, and their clinical characteristics recorded.
Four patients were female, and the mean age was 74.5±16.9 years. Three patients had visual loss secondary to eye disease and three due to cerebral lesions. The visions consisted of animals, persons, moving objects, bizarre creatures or colored forms, and were considered disturbing by five patients. Five patients received treatment, and only three reported partial benefit from the therapy. Complete recovery was not seen in any of the subjects.
CBS is relatively rare and its recognition is important to avoid misdiagnoses with psychiatric or dementing illnesses.
自1760年首次被描述以来,查尔斯·邦尼特综合征(CBS)已在许多研究中被报道。其主要特征为视幻觉、对虚幻视觉的意识保留以及无精神症状。CBS可发生于从眼睛到距状裂的中枢视觉通路沿线任何部位的病变。
描述CBS患者并对文献进行综述。
2001年至2008年间,在一家门诊记忆诊所对6名有视幻觉的患者进行了评估,并记录了他们的临床特征。
4名患者为女性,平均年龄为74.5±16.9岁。3名患者因眼部疾病继发视力丧失,3名因脑部病变。幻觉包括动物、人物、移动物体、奇异生物或彩色图形,5名患者认为这些幻觉令人不安。5名患者接受了治疗,只有3名报告治疗有部分益处。所有受试者均未完全康复。
CBS相对罕见,认识到它对于避免与精神疾病或痴呆症的误诊很重要。