加拿大海洋省份 HIV/AIDS 患者的大麻使用模式和相关因素。
Patterns and correlates of cannabis use among individuals with HIV/AIDS in Maritime Canada.
机构信息
Faculty of Education, Memorial University of Newfoundland, St John's, Newfoundland and Labrador;
Horizon Health Network, Moncton, New Brunswick;
出版信息
Can J Infect Dis Med Microbiol. 2014 Spring;25(1):e1-7. doi: 10.1155/2014/301713.
BACKGROUND
The prevalence of cannabis use in HIV-infected individuals is high and its long-term effects are unclear.
METHODS
The prevalence, perceived benefits and consequences, and predictors of cannabis use were studied using a cross-sectional survey in two immunodeficiency clinics in Maritime Canada.
RESULTS
Current cannabis use was identified in 38.5% (87 of 226) of participants. Almost all cannabis users (85 of 87 [97.7%]) acknowledged its use for recreational purposes, with 21.8% (19 of 87) reporting medicinal cannabis use. The majority of patients enrolled in the present study reported mild or no symptoms related to HIV (n=179). Overall, 80.5% (70 of 87) of the cannabis-using participants reported a symptom-relieving benefit, mostly for relief of stress, anorexia or pain. Participants consumed a mean (± SD) of 18.3±21.1 g of cannabis per month and spent an average of $105.15±109.87 on cannabis per month. Cannabis use was associated with rural residence, lower income level, driving under the influence of a substance, and consumption of ecstasy and tobacco. Income level, ecstasy use and tobacco use were retained as significant predictors in regression modelling. Cannabis use was not associated with adverse psychological outcomes.
DISCUSSION
Prolonged previous cannabis consumption and the substantial overlap between recreational and medicinal cannabis use highlight the challenges in obtaining a tenable definition of medicinal cannabis therapy.
背景
在感染 HIV 的个体中，大麻使用的流行率很高，其长期影响尚不清楚。
方法
在加拿大海洋省的两个免疫缺陷诊所，通过横断面调查研究了大麻使用的流行率、感知益处和后果，以及预测因素。
结果
在 226 名参与者中，有 38.5%（87 人）存在当前大麻使用情况。几乎所有大麻使用者（87 人中有 85 人[97.7%]）都承认其为娱乐目的而使用大麻，21.8%（87 人中有 19 人）报告使用医用大麻。本研究中大多数入组患者报告与 HIV 相关的症状轻微或无（n=179）。总体而言，80.5%（87 名大麻使用者中有 70 人）报告了症状缓解的益处，主要是缓解压力、厌食或疼痛。参与者每月平均（± SD）消费 18.3±21.1 克大麻，每月平均花费 105.15±109.87 美元用于大麻。大麻使用与农村居住、较低的收入水平、受物质影响下驾驶以及摇头丸和烟草的使用有关。收入水平、摇头丸使用和烟草使用是回归模型中保留的显著预测因素。大麻使用与不良心理结果无关。
讨论
长期以往的大麻使用以及娱乐性和医用大麻使用之间的大量重叠，突显了获得可行的医用大麻疗法定义的挑战。
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