Fisher Sherri L, Bucholz Kathleen K, Reich Wendy, Fox Louis, Kuperman Samuel, Kramer John, Hesselbrock Victor, Dick Danielle M, Nurnberger John I, Edenberg Howard J, Bierut Laura J
Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Alcohol Clin Exp Res. 2006 Oct;30(10):1699-710. doi: 10.1111/j.1530-0277.2006.00205.x.
Previous studies have shown that when assessing child psychopathology, parents tend to report more symptoms than children for externalizing disorders such as attention deficit hyperactivity disorder (ADHD), whereas children tend to report more symptoms for internalizing disorders such as major depression. Whether for clinical or research purposes, parents are also frequently asked to report on their children's experiences with alcohol and drugs. The purpose of this study was to analyze correspondence between adolescent and parent reports of adolescent substance use and abuse or dependence.
In the current study, 591 subjects 12 to 17 years old were interviewed using the child version of the Semi-Structured Assessment for the Genetics of Alcoholism (C-SSAGA) as part of the Collaborative Study on the Genetics of Alcoholism (COGA). One parent was also interviewed about each adolescent using the parent version of the C-SSAGA. Sensitivities, specificities, and kappa coefficients were calculated to assess parental agreement with adolescent reports of lifetime substance use and Diagnostic and Statistical Manual of Mental Disorders-Third Revision substance abuse or dependence.
The results indicate that parents are somewhat knowledgeable about their children's use of substances, particularly those that are used most commonly. For example, 55% of adolescents who had smoked cigarettes, 50% who had used alcohol, and 47% who had used marijuana had a parent who knew that they used. However, parents were less aware of substance-related problems experienced by their offspring, agreeing with adolescent reports only 27% of the time for diagnoses of alcohol abuse or dependence and 26% of the time for diagnoses of marijuana abuse or dependence. Parent reports added few cases of substance use for 12- to 13 year-olds and essentially no cases for 16- to 17-year-olds. Parent reports added a nominal number of diagnoses of substance abuse or dependence for older adolescents.
Whether for clinical or research purposes, the results emphasize the importance of directly assessing adolescents regarding alcohol and other substance use disorders. Furthermore, investigators should consider the specific disorder(s) being investigated and the ages of the children being studied when determining whether to include parent reports as part of study design.
以往研究表明,在评估儿童精神病理学状况时,对于诸如注意力缺陷多动障碍(ADHD)等外化性障碍,父母倾向于比孩子报告更多症状;而对于诸如重度抑郁等内化性障碍,孩子倾向于报告更多症状。无论是出于临床还是研究目的,父母也经常被要求报告其子女的酒精和药物使用经历。本研究的目的是分析青少年与父母关于青少年物质使用、滥用或依赖报告之间的一致性。
在本研究中,作为酒精中毒遗传学合作研究(COGA)的一部分,使用儿童版酒精中毒遗传学半结构化评估(C - SSAGA)对591名12至17岁的受试者进行了访谈。还使用C - SSAGA的父母版对每位青少年的一位家长进行了访谈。计算敏感性、特异性和kappa系数,以评估父母与青少年关于终生物质使用以及《精神疾病诊断与统计手册》第三版物质滥用或依赖报告的一致性。
结果表明,父母对其子女的物质使用情况有所了解,尤其是那些最常用的物质。例如,吸烟的青少年中有55%、饮酒的青少年中有50%、使用大麻的青少年中有47%的父母知道他们使用这些物质。然而,父母对其子女经历的与物质相关问题了解较少,对于酒精滥用或依赖的诊断,仅27%的时间与青少年报告一致;对于大麻滥用或依赖的诊断,仅26%的时间与青少年报告一致。父母的报告增加了少量12至13岁儿童物质使用的案例,而对于16至17岁的儿童基本上没有增加案例。对于年龄较大的青少年,父母的报告增加了少量物质滥用或依赖的诊断案例。
无论是出于临床还是研究目的,结果都强调了直接评估青少年酒精和其他物质使用障碍的重要性。此外,研究人员在确定是否将父母报告纳入研究设计时,应考虑所研究的特定障碍以及所研究儿童的年龄。