Nose Hiroyuki, Foo Keong Tatt, Lim Kok Bin, Yokoyama Teruhiko, Ozawa Hideo, Kumon Hiromi
Department of Urology, Singapore General Hospital, Singapore, Singapore.
Urology. 2005 Mar;65(3):493-7. doi: 10.1016/j.urology.2004.10.014.
We assessed the accuracy of two noninvasive, ultrasound methods of diagnosing bladder outlet obstruction (BOO). The potential for the combined methods to enhance the accuracy of diagnosis was also assessed.
We evaluated 30 male outpatients using two recently developed diagnostic methods, transabdominal ultrasound grading of intravesical prostatic protrusion (IPP) and Doppler ultrasound urodynamics (Doppler UDS), as well as conventional pressure flow studies according to the research protocol. IPP has been reported to be a useful anatomic parameter for the assessment of BOO. Doppler UDS uses transperineal ultrasonography to measure the velocity flow of urine at the prostatic and sphincteric urethras. We recruited 168 outpatients; however, of the 57 patients who fulfilled all the research criteria, only 30 were able to undergo conventional pressure flow study analysis. The results of all three diagnostic methods were analyzed statistically for reliability and relationship in the 30 patients with a BOO index from the conventional pressure flow study.
IPP grading correlated well with the BOO index (Spearman's rho 0.624), as did the Doppler UDS parameter (Spearman's rho 0.736). The combination of IPP grading and Doppler UDS showed good sensitivity and specificity.
We confirmed the accuracy of the two novel methods. The combination of the two methods may be a novel standard in the diagnosis of BOO in male patients.
我们评估了两种非侵入性超声方法诊断膀胱出口梗阻(BOO)的准确性。还评估了联合使用这两种方法提高诊断准确性的潜力。
我们按照研究方案,使用两种最近开发的诊断方法,即经腹超声评估膀胱内前列腺突出(IPP)分级和多普勒超声尿动力学(多普勒UDS),以及传统的压力流研究,对30名男性门诊患者进行了评估。据报道,IPP是评估BOO的一个有用的解剖学参数。多普勒UDS使用经会阴超声测量前列腺尿道和括约肌尿道的尿流速度。我们招募了168名门诊患者;然而,在满足所有研究标准的57名患者中,只有30名能够接受传统的压力流研究分析。对这30名通过传统压力流研究得出BOO指数的患者,对所有三种诊断方法的结果进行了统计学分析,以评估其可靠性和相关性。
IPP分级与BOO指数相关性良好(Spearman等级相关系数为0.624),多普勒UDS参数也是如此(Spearman等级相关系数为0.736)。IPP分级和多普勒UDS的联合使用显示出良好的敏感性和特异性。
我们证实了这两种新方法的准确性。这两种方法的联合使用可能成为男性患者BOO诊断的一种新的标准。