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The effect of sedation with propofol on postoperative bronchoconstriction in patients with hyperreactive airway disease.

作者信息

Pedersen C M

机构信息

Department of Anaesthesiology and Intensive Care, Skejby University Hospital, Aarhus, Denmark.

出版信息

Intensive Care Med. 1992;18(1):45-6. doi: 10.1007/BF01706426.

DOI:10.1007/BF01706426
PMID:1578048
Abstract

Two patients with chronic obstructive pulmonary disease developed postoperatively bronchospasm after insertion of a prostetic aortic valve. Continuous sedation with propofol infusion was associated with a significant decline in peak inspiratory pressure suggesting that propofol may have bronchodilating properties.

摘要

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Propofol. An overview of its pharmacology and a review of its clinical efficacy in intensive care sedation.丙泊酚。其药理学概述及在重症监护镇静中临床疗效的综述。

本文引用的文献

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Intensive Care Med. 1993;19(5):305. doi: 10.1007/BF01690555.
6
The effect of sedation with propofol on postoperative bronchoconstriction in patients with hyperactive airway disease.丙泊酚镇静对气道高反应性疾病患者术后支气管收缩的影响。
Intensive Care Med. 1992;18(8):498. doi: 10.1007/BF01708593.
4
Comparison of induction characteristics of four intravenous anaesthetic agents.四种静脉麻醉药诱导特性的比较。
Anaesthesia. 1986 Oct;41(10):995-1000. doi: 10.1111/j.1365-2044.1986.tb12740.x.
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Pharmacokinetic implications for the clinical use of propofol.丙泊酚临床应用的药代动力学影响
Clin Pharmacokinet. 1989 Nov;17(5):308-26. doi: 10.2165/00003088-198917050-00002.
6
An in-vitro study of the interactions between intravenous induction agents and the calcium antagonists verapamil and nifedipine.静脉诱导剂与钙拮抗剂维拉帕米和硝苯地平相互作用的体外研究。
J Pharm Pharmacol. 1989 Dec;41(12):840-3. doi: 10.1111/j.2042-7158.1989.tb06383.x.
7
Vascular effects of propofol: smooth muscle relaxation in isolated veins and arteries.丙泊酚的血管效应：对离体静脉和动脉平滑肌的舒张作用
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Comparison of propofol and midazolam for sedation in critically ill patients.丙泊酚与咪达唑仑用于重症患者镇静的比较。
Lancet. 1989 Sep 23;2(8665):704-9. doi: 10.1016/s0140-6736(89)90770-8.
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Comparison of the effects of fentanyl on respiratory mechanics under propofol or thiopental anaesthesia.丙泊酚或硫喷妥钠麻醉下芬太尼对呼吸力学影响的比较。
Acta Anaesthesiol Scand. 1990 May;34(4):253-6. doi: 10.1111/j.1399-6576.1990.tb03080.x.
10
Propofol sedation after open heart surgery. A clinical and pharmacokinetic study.心脏直视手术后的丙泊酚镇静：一项临床与药代动力学研究
Anaesthesia. 1990 Apr;45(4):322-6. doi: 10.1111/j.1365-2044.1990.tb14743.x.