Hooper S M, Hughes J A, Newcombe R G, Addy M, West N X
Division of Restorative Dentistry, Department of Oral and Dental Science, Bristol Dental Hospital, University of Bristol, Lower Maudlin Street, Bristol BS1 2LY, UK.
J Dent. 2005 Apr;33(4):343-8. doi: 10.1016/j.jdent.2004.10.002. Epub 2004 Dec 25.
The aim of the study was to develop and test a methodology in situ, which simulated the consumption of sports drinks. A secondary aim was to assess the acceptability of the method to sedentary participants.
To select the sports drink for the study in situ, five commercially available sports drinks were examined for erosive potential in vitro. The study in situ was a single centre, 2-period, 2-treatment crossover study to compare the erosive effect of a commercially available sports drink (Test), with that of mineral water (Control), over 10 day periods on 10 healthy volunteers. Subjects wore upper removable appliances containing two human enamel specimens from 9 a.m. to 5 p.m. The regimen of intake of the drinks was 350 ml in 10, 5-min rest, 650 ml in 25, 5-min rest, 500 ml in 10 and 5-min rest. Measurements of enamel loss were made on samples after 5 and 10 days by profilometry.
The in situ study showed a statistically significant difference in erosive potential between the test and control beverages. No specimen exposed to the control beverage displayed appreciable erosion. Erosion occurred with the test drink, but to a variable degree between subjects. The subjects unanimously found the drinking regimen unpleasant.
The sports drink caused significantly more erosion in situ than water and as seen in other studies, there was marked variation in susceptibility to erosion between subjects. The new drinking regimen was designed to simulate pre, during and post-exercise intake. Although all the sedentary subjects participating in this study reported that they found the volume of fluids consumed over a short period of time excessive it is unlikely that this would prove problematic in the exercise environment.
本研究旨在开发并现场测试一种模拟运动饮料饮用情况的方法。次要目的是评估该方法对久坐不动的参与者的可接受性。
为了在现场研究中选择运动饮料,对五种市售运动饮料的体外侵蚀潜力进行了检测。现场研究是一项单中心、两阶段、两治疗组的交叉研究,在10天内比较一种市售运动饮料(测试组)与矿泉水(对照组)对10名健康志愿者的侵蚀作用。受试者从上午9点到下午5点佩戴含有两个人类牙釉质标本的上可摘矫治器。饮料摄入方案为在10次5分钟休息期间饮用350毫升,在25次5分钟休息期间饮用650毫升,在10次5分钟休息期间饮用500毫升。在第5天和第10天后通过轮廓仪对样本进行牙釉质损失测量。
现场研究表明,测试饮料和对照饮料在侵蚀潜力方面存在统计学上的显著差异。暴露于对照饮料的标本均未显示出明显的侵蚀。测试饮料导致了侵蚀,但受试者之间的侵蚀程度各不相同。受试者一致认为饮用方案令人不适。
运动饮料在现场造成的侵蚀明显多于水,并且正如其他研究中所见,受试者之间的侵蚀易感性存在显著差异。新制定的饮用方案旨在模拟运动前、运动中和运动后的摄入量。尽管参与本研究的所有久坐不动的受试者均表示,他们认为在短时间内摄入的液体量过多,但在运动环境中这不太可能成为问题。