Hooper S, Hughes J, Parker D, Finke M, Newcombe R G, Addy M, West N
Division of Restorative Dentistry, Bristol Dental School, Lower Maudlin Street, Bristol BS1 2LY, UK.
J Dent. 2007 Jun;35(6):541-6. doi: 10.1016/j.jdent.2007.03.001. Epub 2007 Apr 24.
The consumption of acidic soft drinks continues to rise as do concerns regarding effects of frequent intake. The aim of the study was to determine the effect of acidic soft drinks containing food approved polymers, on dental enamel.
The study design was a single blind, randomised, five-treatment crossover clinical trial involving 15 healthy dentate subjects. Subjects wore an upper removable acrylic appliance retaining two enamel specimens and consumed 250ml of beverage four times/day for 10 days. The following beverages were tested: (1) unmodified acidic soft drink, (2) experimental acidic soft drink with 0.02% polyphosphate, (3) experimental acidic soft drink with 0.02% polyphosphate and 0.01% calcium, (4) experimental acidic soft drink with 0.02% polyphosphate and 0.03% xanthan gum, and (5) mineral water. Tissue loss was measured at days 5 and 10 of each study leg using a profilometer.
The order of erosion from most to least at day 10 was unmodified acidic soft drink>experimental acidic soft drink with polyphosphate>experimental acidic soft drink with polyphosphate+gum>experimental acidic soft drink with polyphosphate+calcium>mineral water. At day 10 the unmodified acidic soft drink was significantly (p=0.001) more erosive than all other drinks.
Unmodified acidic soft drink with the addition of polyphosphate alone or combined with calcium or xanthan gum are all effective at reducing erosion of enamel compared with the unmodified soft acidic drink.
酸性软饮料的消费量持续上升，人们对频繁饮用的影响也日益担忧。本研究的目的是确定含有食品批准聚合物的酸性软饮料对牙釉质的影响。
本研究设计为单盲、随机、五处理交叉临床试验，涉及15名健康有牙受试者。受试者佩戴一个上部可摘丙烯酸矫治器，其中保留两个牙釉质标本，每天饮用250毫升饮料4次，共10天。测试了以下饮料：（1）未改良的酸性软饮料，（2）含0.02%多磷酸盐的实验性酸性软饮料，（3）含0.02%多磷酸盐和0.01%钙的实验性酸性软饮料，（4）含0.02%多磷酸盐和0.03%黄原胶的实验性酸性软饮料，以及（5）矿泉水。在每个研究阶段的第5天和第10天，使用轮廓仪测量组织损失。
在第10天，侵蚀程度从高到低的顺序为：未改良的酸性软饮料>含多磷酸盐的实验性酸性软饮料>含多磷酸盐+黄原胶的实验性酸性软饮料>含多磷酸盐+钙的实验性酸性软饮料>矿泉水。在第10天，未改良的酸性软饮料的侵蚀性显著高于所有其他饮料（p=0.001）。
与未改良的酸性软饮料相比，单独添加多磷酸盐或与钙或黄原胶混合的未改良酸性软饮料在减少牙釉质侵蚀方面均有效。
