Costello Michael F
University of New South Wales.
Aust Fam Physician. 2005 Mar;34(3):127-33.
Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women and is associated with both reproductive and metabolic disorders.
This article discusses the health risks, clinical assessment and investigations consistent with the new internationally agreed definition of PCOS, available treatments, and the long-term monitoring of women with PCOS.
Women with PCOS have an increased risk of endometrial carcinoma, type 2 diabetes mellitus, and possibly cardiovascular disease. Polycystic ovary syndrome is a diagnosis of exclusion of other causes of hyperandrogenism. Screening for diabetes is important. Treatment is directed at the presenting symptom as the primary cause is unknown. Long-term medical treatment may include the oral contraceptive pill or metformin. Long-term surveillance is recommended for the early detection and treatment of potential metabolic complications.
多囊卵巢综合征(PCOS)是女性中最常见的内分泌疾病,与生殖和代谢紊乱均有关联。
本文讨论与新的国际公认的PCOS定义相符的健康风险、临床评估与检查、可用治疗方法以及PCOS女性的长期监测。
PCOS女性患子宫内膜癌、2型糖尿病以及可能患心血管疾病的风险增加。多囊卵巢综合征是排除其他高雄激素血症病因后的诊断。糖尿病筛查很重要。由于主要病因不明,治疗针对当前症状。长期药物治疗可能包括口服避孕药或二甲双胍。建议进行长期监测以早期发现和治疗潜在的代谢并发症。