Paavilainen Ville, Tuominen Juhani, Pukkala Eero, Saari K Matti
Department of Ophthalmology, University of Turku, Turku, Finland.
Acta Ophthalmol Scand. 2005 Apr;83(2):215-20. doi: 10.1111/j.1600-0420.2005.00445.x.
To study the incidence of basal cell carcinoma (BCC) of the eyelid in Finland.
We studied 6241 cases of BCC of the eyelid reported to the nationwide Finnish Cancer Registry during 1953-97. We determined the age- and sex- specific incidence rates and overall rates adjusted for age to the world standard population, and social class- and occupation-specific standardized incidence ratios, with the total Finnish population as reference.
The incidence rates of BCC of the eyelid varied between 0.7 and 3.0 per 100 000 person-years in men and between 0.5 and 2.8 per 100 000 person-years in women during the study period. The age-adjusted incidence rates of BCC of the eyelid increased during 1953-87 (p < 0.0001). The incidence of BCC of the eyelid rose significantly with age. There were no significant differences in standardized incidence ratios (SIRs) for BCC of the eyelid between different social class and occupation categories.
Age-adjusted incidence rates showed that BCC of the eyelid was more than twice as frequent during 1978-97 than before 1968. Ageing may partly explain the increased incidence of BCC of the eyelid, whereas there were no differences in the SIRs for BCC of the eyelid between different social class and occupation categories in Finland.
研究芬兰眼睑基底细胞癌(BCC)的发病率。
我们研究了1953年至1997年间向芬兰全国癌症登记处报告的6241例眼睑BCC病例。我们确定了年龄和性别特异性发病率以及根据世界标准人口年龄调整后的总体发病率,以及以芬兰总人口为参考的社会阶层和职业特异性标准化发病率。
在研究期间,男性眼睑BCC的发病率在每10万人年0.7至3.0之间,女性在每10万人年0.5至2.8之间。1953年至1987年间,眼睑BCC的年龄调整发病率有所上升(p < 0.0001)。眼睑BCC的发病率随年龄显著上升。不同社会阶层和职业类别的眼睑BCC标准化发病率(SIR)没有显著差异。
年龄调整发病率显示,1978年至1997年间眼睑BCC的发病率是1968年以前的两倍多。老龄化可能部分解释了眼睑BCC发病率的上升,而芬兰不同社会阶层和职业类别的眼睑BCC的SIR没有差异。