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采用一种新的试纸条法测量胎儿头皮和脐动脉血乳酸。

Fetal scalp and umbilical artery blood lactate measured with a new test strip method.

作者信息

Nordström L, Persson B, Shimojo N, Westgren M

机构信息

St. Görans Pediatric Hospital Karolinska Institutet, Sweden.

出版信息

Br J Obstet Gynaecol. 1992 Apr;99(4):307-9. doi: 10.1111/j.1471-0528.1992.tb13728.x.

Abstract

OBJECTIVE

To compare the measurement of lactate in fetal scalp and umbilical artery blood by a new dry reagent strip method with a commercially available enzymatic method using plasma (Monotest).

DESIGN

Comparative study.

SUBJECTS

Fetal scalp blood samples were obtained during labour from 24 fetuses and umbilical artery blood samples were obtained at birth in a further 51 deliveries.

RESULTS

The concentration of lactate in scalp and umbilical artery blood measured by the reagent strip method correlated well (r = 0.94, P less than 0.001 and 0.95, P less than 0.001 respectively) with the enzymatic plasma method. The paper strip method tended to give lower readings than the enzymatic method when the fetal haematocrit was greater than or equal to 50%.

CONCLUSIONS

The new dry reagent strip method which takes only 1 min to carry out and requires only 20 microliters of blood seems to be handy and reliable. This system provides a convenient and rapid test for measuring fetal blood lactate.

摘要

目的

采用一种新的干试剂条法与一种市售的使用血浆的酶法(Monotest)比较胎儿头皮血和脐动脉血中乳酸的测定结果。

设计

对比研究。

对象

在分娩过程中从24例胎儿获取胎儿头皮血样本,另外在51例分娩时获取脐动脉血样本。

结果

用试剂条法测得的头皮血和脐动脉血中乳酸浓度与酶法血浆测定结果相关性良好(分别为r = 0.94,P < 0.001和r = 0.95,P < 0.001)。当胎儿血细胞比容大于或等于50%时,纸条法测得的读数往往低于酶法。

结论

这种新的干试剂条法仅需1分钟完成,仅需20微升血液,似乎方便且可靠。该系统为测量胎儿血乳酸提供了一种便捷快速的检测方法。

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