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DPC IMMULITE 1000上促卵泡生成素、促黄体生成素、雌二醇、三碘甲状腺原氨酸、游离三碘甲状腺原氨酸、皮质醇和生长激素的儿科参考区间。

Pediatric reference intervals for FSH, LH, estradiol, T3, free T3, cortisol, and growth hormone on the DPC IMMULITE 1000.

作者信息

Soldin Offie P, Hoffman Eve G, Waring Michael A, Soldin Steven J

机构信息

Division of Endocrinology and Metabolism, Georgetown University School of Medicine, Washington DC 20057-1465, USA.

出版信息

Clin Chim Acta. 2005 May;355(1-2):205-10. doi: 10.1016/j.cccn.2005.01.006.

Abstract

BACKGROUND

We studied serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), triiodothyronine (T3), free T3 (FT3), cortisol and growth hormone (GH) concentrations in a population of pediatric patients. The reference intervals were determined separately for females and males stratified by age groups to assess age- and sex-related differences. Our objective was to obtain reference intervals for the 7 serum analytes for our pediatric population using the IMMULITE 1000 system.

METHODS

Serum samples of 800 in- and out-patients, newborn to 19 years old were analyzed using the DPC IMMULITE 1000 chemiluminescent immunoassay system.

RESULTS AND CONCLUSIONS

We report pediatric reference intervals for FSH, LH, E2, T3, FT3, cortisol, and GH. These reference intervals provide the basis for clinical interpretation of laboratory results using the IMMULITE 1000 system and the assessment of child development.

摘要

背景

我们研究了一组儿科患者血清中促卵泡生成素(FSH)、促黄体生成素(LH)、雌二醇(E2)、三碘甲状腺原氨酸(T3)、游离T3(FT3)、皮质醇和生长激素(GH)的浓度。通过按年龄组对女性和男性进行分层,分别确定参考区间,以评估年龄和性别相关差异。我们的目标是使用IMMULITE 1000系统获得我们儿科人群7种血清分析物的参考区间。

方法

使用DPC IMMULITE 1000化学发光免疫分析系统对800例年龄从新生儿到19岁的住院和门诊患者的血清样本进行分析。

结果与结论

我们报告了FSH、LH、E2、T3、FT3、皮质醇和GH的儿科参考区间。这些参考区间为使用IMMULITE 1000系统对实验室结果进行临床解释以及评估儿童发育提供了依据。

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