Jia Haomiao, Lubetkin Erica I
Department of Community Medicine, Mercer University School of Medicine, 1550 College Street, Macon, GA 31207, USA.
J Public Health (Oxf). 2005 Jun;27(2):156-64. doi: 10.1093/pubmed/fdi025. Epub 2005 Apr 8.
The US Preventive Services Task Force recently recommended screening all adult patients for obesity due in part to the strong association between obesity and numerous chronic diseases. However, how obesity affects health-related quality-of-life (HRQL), particularly for persons without any chronic diseases, is less clear.
The relationship between obesity and HRQL was examined using data from the 2000 Medical Expenditure Panel Survey. Respondents > or =18 years were classified as underweight, normal weight, overweight, class I obesity, and class II obesity based on their BMI. HRQL was measured by the 12-item Short Form physical and mental summary scores (PCS-12 and MCS-12, respectively) and EuroQol EQ-5D index and visual analogue scale (EQ VAS). The impact of obesity on HRQL was examined through multivariate regression, adjusting for sociodemographics and disease status.
After adjustment, HRQL decreased with increasing level of obesity. Compared to normal weight respondents, persons with severe obesity had significantly lower scores with scores on the PCS-12, MCS-12, EQ-5D index, and EQ VAS being 4.0, 1.1, 0.073, and 4.8 points lower, respectively. Such decrements of HRQL for severe obesity were similar to the decrements seen for diabetes or hypertension. Persons with moderate obesity or who were overweight also had significantly lower HRQL scores, particularly on the PCS-12 and EQ-5D index. Underweight persons also had lower MCS-12 and EQ VAS scores.
Persons with obesity had significantly lower HRQL than those who were normal weight and such lower scores were seen even for persons without chronic diseases known to be linked to obesity.
美国预防服务工作组最近建议对所有成年患者进行肥胖筛查，部分原因是肥胖与众多慢性疾病之间存在密切关联。然而，肥胖如何影响健康相关生活质量（HRQL），尤其是对于没有任何慢性疾病的人，尚不清楚。
使用2000年医疗支出小组调查的数据研究肥胖与HRQL之间的关系。根据体重指数（BMI），将年龄≥18岁的受访者分为体重过轻、正常体重、超重、I类肥胖和II类肥胖。HRQL通过12项简短形式身体和心理总结评分（分别为PCS - 12和MCS - 12）以及欧洲五维度健康量表（EuroQol EQ - 5D）指数和视觉模拟量表（EQ VAS）进行测量。通过多变量回归分析肥胖对HRQL的影响，并对社会人口统计学和疾病状况进行调整。
调整后，HRQL随着肥胖程度的增加而降低。与正常体重的受访者相比，重度肥胖者的得分显著更低，PCS - 12、MCS - 12、EQ - 5D指数和EQ VAS得分分别低4.0、1.1、0.073和4.8分。重度肥胖导致的HRQL下降幅度与糖尿病或高血压患者的下降幅度相似。中度肥胖或超重者的HRQL得分也显著更低，尤其是在PCS - 12和EQ - 5D指数上。体重过轻者的MCS - 12和EQ VAS得分也较低。
肥胖者的HRQL显著低于正常体重者，即使是没有已知与肥胖相关慢性疾病的人也有较低的得分。
