瑞典斯德哥尔摩迟发性皮肤卟啉症患者中丙型肝炎的患病率。

The prevalence of hepatitis C in patients with porphyria cutanea tarda in Stockholm, Sweden.

作者信息

Linde Ylva, Harper Pauline, Floderus Ylva, Ros Anne-Marie

机构信息

Department of Dermatology, Karolinska Institute at Stockholm Söder Hospital, SE118 83 Stockholm, Sweden.

出版信息

Acta Derm Venereol. 2005;85(2):164-6. doi: 10.1080/00015550410023518.

DOI:10.1080/00015550410023518

PMID:15823914

Abstract

In many countries hepatitis C virus infection has been considered a major factor triggering overt porphyria cutanea tarda. The prevalence of hepatitis C virus infection was retrospectively studied in 87 patients who during a period of 11 years were diagnosed with porphyria cutanea tarda in Stockholm. Among patients with the sporadic form of porphyria cutanea tarda, the prevalence of hepatitis C virus infection was 36.4%. As hepatitis C virus infection may today be successfully treated and as the infection may be clinically silent and thus unknown to the patient, it is important to screen all patients with porphyria cutanea tarda for hepatitis C virus infection.

摘要

在许多国家，丙型肝炎病毒感染被认为是引发迟发性皮肤卟啉症显性发作的一个主要因素。对87例在11年期间于斯德哥尔摩被诊断为迟发性皮肤卟啉症的患者，回顾性研究了丙型肝炎病毒感染的患病率。在散发性迟发性皮肤卟啉症患者中，丙型肝炎病毒感染的患病率为36.4%。鉴于如今丙型肝炎病毒感染可以得到成功治疗，且该感染在临床上可能没有症状，因而患者可能并不知晓，所以对所有迟发性皮肤卟啉症患者进行丙型肝炎病毒感染筛查很重要。