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迟发性皮肤卟啉症与丙型肝炎病毒感染

[Porphyria cutanea tarda and hepatitis C virus infection].

作者信息

Held E, Petersen C S

机构信息

Dermato-venerologisk afdeling, Bispebjerg Hospital.

出版信息

Ugeskr Laeger. 1997 Feb 24;159(9):1284-6.

PMID:9072876
Abstract

Porphyria cutanea tarda (PCT) is a rare metabolic disorder characterized by an abnormal porphyrin metabolism and typical cutaneous lesions. Recently a strong association between PCT and hepatitis C virus (HCV) has been proposed. Studies in the south of Europe have shown high prevalences (53 to 91%) of HCV markers in patients with sporadic PCT. Six characteristic case stories are presented. We suggest routine hepatitis C serological testing in all patients with PCT, as HCV infection is a major predisposing factor for the disease.

摘要

迟发性皮肤卟啉症(PCT)是一种罕见的代谢紊乱疾病,其特征为卟啉代谢异常和典型的皮肤病变。最近有人提出PCT与丙型肝炎病毒(HCV)之间存在密切关联。欧洲南部的研究表明,散发性PCT患者中HCV标志物的患病率很高(53%至91%)。本文介绍了六个典型病例。我们建议对所有PCT患者进行常规丙型肝炎血清学检测,因为HCV感染是该疾病的主要诱发因素。

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