Martínez Juan Pablo, Olmos Salvador
Communications Technology Group, Aragon Institute of Engineering Research, University of Zaragoza, Maria de Luna, 1, 50018 Zaragoza, Spain.
IEEE Trans Biomed Eng. 2005 Apr;52(4):599-613. doi: 10.1109/TBME.2005.844025.
Visible T wave alternans (TWA) in the electrocardiogram (ECG) had been regarded as an infrequent phenomenon during the first 80 years of electrocardiography. Nevertheless, computerized analysis changed this perception. In the last two decades, a variety of techniques for automatic TWA analysis have been proposed. These techniques have allowed researchers to detect nonvisible TWA in a wide variety of clinical and experimental conditions. Such studies have recently shown that TWA is related to cardiac instability and increased arrhythmogenicity. Comparison of TWA analysis methods is a difficult task due to the diversity of approaches. In this paper, we propose a unified framework which holds the existing methods. In the light of this framework, the methodological principles of the published TWA analysis schemes are compared and discussed. This framework may have an important role to develop new approaches to this problem.
在心电图（ECG）发展的最初80年里，心电图中可见的T波交替（TWA）一直被视为一种罕见现象。然而，计算机分析改变了这一观念。在过去二十年中，人们提出了多种自动分析TWA的技术。这些技术使研究人员能够在各种临床和实验条件下检测到不可见的TWA。最近的此类研究表明，TWA与心脏不稳定和心律失常性增加有关。由于方法的多样性，比较TWA分析方法是一项艰巨的任务。在本文中，我们提出了一个统一的框架来涵盖现有方法。基于这个框架，对已发表的TWA分析方案的方法学原理进行了比较和讨论。这个框架可能在开发解决此问题的新方法方面发挥重要作用。
