Curcio D, Belloni R
Infectious Diseases Service, Sanatorio Güemes, Buenos Aires, Argentina.
J Chemother. 2005 Feb;17(1):74-6. doi: 10.1179/joc.2005.17.1.74.
There is a general consensus that antimicrobial use in intensive care units (ICU) is greater than that in general wards. By implementing a strategy of systematic infectious disease consultations in agreement with the ICU chief, we have modified the antibiotic prescription habits of the ICU physician. A reduction was observed in the use of selected antibiotics (third-generation cephalosporins, vancomycin, carbapenems and piperacillin-tazobactam), with a significant reduction in the length of hospital stay for ICU patients and lower antibiotic costs without negative impact on patient mortality. Leadership by the infectious diseases consultant in combination with commitment by ICU physicians is a simple and effective method to change antibiotic prescription habits in the ICU.
人们普遍认为，重症监护病房（ICU）的抗菌药物使用量高于普通病房。通过与ICU主任达成一致实施系统性传染病会诊策略，我们改变了ICU医生的抗生素处方习惯。观察到某些选定抗生素（第三代头孢菌素、万古霉素、碳青霉烯类和哌拉西林-他唑巴坦）的使用量有所减少，ICU患者的住院时间显著缩短，抗生素成本降低，且对患者死亡率没有负面影响。传染病顾问的引领与ICU医生的投入相结合，是改变ICU抗生素处方习惯的一种简单而有效的方法。
