[痴呆症患者对疾病的认知：轻度和中度阿尔茨海默病患者的初步结果]
[Awareness of disease in dementia: preliminary results in patients with mild and moderate Alzheimer's disease].
作者信息
Dourado Márcia, Laks Jerson, Rocha Marlos, Soares Claudia, Leibing Annette, Engelhardt Eliasz
机构信息
IPUB, Universidade Federal do Rio de Janeiro, RJ, Brazil.
出版信息
Arq Neuropsiquiatr. 2005 Mar;63(1):114-8. doi: 10.1590/s0004-282x2005000100021. Epub 2005 Apr 13.
OBJECTIVE
To evaluate the presence and the level of awareness of disease in mild and moderate Alzheimer's disease (AD).
METHOD
Cross-sectional evaluation of patients with mild/moderate AD (n=42) assessed by Assessment of Psychosocial Impact of the Dementia Diagnosis (APSID), Mini-mental State Examination (MMSE) and Clinical Dementia Rating Scale (CDR).
RESULTS
Awareness of disease and its consequences were present in 66.7% patients with mild AD (n=18). In moderate AD (n=24), 20.8% presented total awareness, 45.8% presented only awareness of cognitive symptoms. Unawareness of disease was observed in 33.3%.
CONCLUSIONS
The present data show association between awareness and level of severity of disease. CDR 1 patients show a better recognition of cognitive and daily life activity symptoms, whereas CDR 2 patients recognized their cognitive symptoms but failed to appraise their severity and consequences in daily life activities.
目的
评估轻度和中度阿尔茨海默病（AD）患者对疾病的知晓情况及其知晓程度。
方法
采用痴呆诊断的社会心理影响评估（APSID）、简易精神状态检查表（MMSE）和临床痴呆评定量表（CDR），对42例轻度/中度AD患者进行横断面评估。
结果
在轻度AD患者（n = 18）中，66.7%知晓疾病及其后果。在中度AD患者（n = 24）中，20.8%完全知晓，45.8%仅知晓认知症状。33.3%的患者对疾病无知晓。
结论
目前的数据表明知晓情况与疾病严重程度之间存在关联。CDR 1级患者对认知和日常生活活动症状的认识较好，而CDR 2级患者虽认识到认知症状，但未评估其严重程度及对日常生活活动的影响。
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