Oliver Brian, Misteli Tom
National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA.
Genome Biol. 2005;6(4):214. doi: 10.1186/gb-2005-6-4-214. Epub 2005 Mar 31.
Recent publications on a wide range of eukaryotes indicate that genes showing particular expression patterns are not randomly distributed in the genome but are clustered into contiguous regions that we call neighborhoods. It seems probable that this organization is related to chromatin and the structure of the nucleus.
近期关于多种真核生物的出版物表明，呈现特定表达模式的基因并非随机分布在基因组中，而是聚集在我们称之为“邻域”的连续区域内。这种组织形式很可能与染色质及细胞核结构有关。
