在一项关于手机使用与脑肿瘤的病例对照研究中，因参与程度不同而导致的选择偏倚。

Selection bias due to differential participation in a case-control study of mobile phone use and brain tumors.

作者信息

Lahkola Anna, Salminen Tiina, Auvinen Anssi

机构信息

STUK-Radiation and Nuclear Safety Authority, FIN-00881 Helsinki, Finland.

出版信息

Ann Epidemiol. 2005 May;15(5):321-5. doi: 10.1016/j.annepidem.2004.12.009.

DOI:10.1016/j.annepidem.2004.12.009

PMID:15840544

Abstract

PURPOSE

To evaluate the possible selection bias related to the differential participation of mobile phone users and non-users in a Finnish case-control study on mobile phone use and brain tumors.

METHODS

Mobile phone use was investigated among 777 controls and 726 cases participating in the full personal interview (full participants), and 321 controls and 103 cases giving only a brief phone interview (incomplete participants). To assess selection bias, the Mantel-Haenszel estimate of odds ratio was calculated for three different groups: full study participants, incomplete participants, and a combined group consisting of both full and incomplete participants.

RESULTS

Among controls, 83% of the full participants and 73% of the incomplete participants had regularly used a mobile phone. Among cases, the figures were 76% and 64%, respectively. The odds ratio for brain tumor based on the combined group of full and incomplete participants was slightly closer to unity than that based only on the full participants.

CONCLUSIONS

Selection bias tends to distort the effect estimates below unity, while analyses based on more comprehensive material gave results close to unity.

摘要

目的

在一项关于手机使用与脑肿瘤的芬兰病例对照研究中，评估与手机使用者和非使用者的差异参与相关的可能选择偏倚。

方法

在参与全面个人访谈的777名对照者和726名病例（完全参与者），以及仅接受简短电话访谈的321名对照者和103名病例（不完全参与者）中调查手机使用情况。为评估选择偏倚，针对三个不同组计算了比值比的Mantel-Haenszel估计值：完整研究参与者、不完全参与者，以及由完整和不完全参与者组成的合并组。