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用莫氏显微外科手术治疗同步性黏液癌和内分泌性黏液生成汗腺癌。

Treatment of synchronous mucinous carcinoma and endocrine mucin-producing sweat gland carcinoma with Mohs' micrographic surgery.

作者信息

Tannous Zeina S, Avram Mathew M, Zembowicz Artur, Mihm Martin C, Liteplo Merrill, Kwan Theodore, Olbricht Suzanne M

机构信息

Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

出版信息

Dermatol Surg. 2005 Mar;31(3):364-7. doi: 10.1111/j.1524-4725.2005.31091.

Abstract

BACKGROUND

Endocrine mucin-producing sweat gland carcinoma is a very rare cutaneous tumor that has been reported only in three patients previously. We report a case of an endocrine mucin-producing sweat gland carcinoma associated with mucinous carcinoma treated by Mohs' micrographic surgery.

OBJECTIVE

The purpose of this report is to test the utility of Mohs' micrographic surgery in the treatment of mucinous carcinomata.

METHODS

A 79-year-old female with a 2-year history of four lesions of biopsy-proven endocrine mucin-producing sweat gland carcinomas and mucinous carcinoma was treated with Mohs' micrographic surgery.

RESULTS

Three of the lesions were completely cleared by Mohs' micrographic surgery. The fourth lesion, in the right lateral canthus, was not cleared by the Mohs' technique because of its location within the orbit and the difficulty of retraction of the globe for appropriate visualization and excision. The patient underwent wide excision of the remaining orbital tumor and reconstruction, which was successfully accomplished. The patient did not experience a recurrence in any of her four lesions over a 2-year follow-up period.

CONCLUSION

Mohs' micrographic surgery is an appropriate treatment for mucinous carcinomata, including endocrine mucin-producing sweat gland carcinoma and mucinous carcinoma.

摘要

背景

内分泌黏液生成性汗腺癌是一种非常罕见的皮肤肿瘤,此前仅有3例病例报道。我们报告1例通过莫氏显微外科手术治疗的内分泌黏液生成性汗腺癌合并黏液腺癌。

目的

本报告旨在检验莫氏显微外科手术在治疗黏液腺癌中的效用。

方法

一名79岁女性,有4处活检证实为内分泌黏液生成性汗腺癌和黏液腺癌的病灶,病史2年,接受了莫氏显微外科手术治疗。

结果

3处病灶通过莫氏显微外科手术完全清除。位于右侧内眦的第4处病灶,由于其位于眼眶内,且难以牵拉眼球以进行适当的可视化和切除,因此莫氏技术未能将其清除。患者接受了剩余眼眶肿瘤的广泛切除及重建,手术成功完成。在2年的随访期内,患者的4处病灶均未复发。

结论

莫氏显微外科手术是治疗黏液腺癌的一种合适方法,包括内分泌黏液生成性汗腺癌和黏液腺癌。

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