National Reporting Centre for Ophthalmic Pathology, Centre for Sight, Hyderabad, India.
Oculoplastics, Facial Aesthetics and Ocular Oncology, Centre for Sight, New Delhi, India.
Indian J Ophthalmol. 2019 Aug;67(8):1374-1377. doi: 10.4103/ijo.IJO_1745_18.
Sweat gland neoplasms are rare adnexal tumors that pose a diagnostic challenge for both, ophthalmologists and pathologists. Endocrine, mucin producing sweat gland carcinoma (EMPSGC), considered to be analogous to the solid papillary mammary carcinoma is one such tumor. It usually affects elderly, is more frequent in women and has a predilection for skin of the eyelid. Although it has an indolent clinical course, EMPSGC is believed to be a precursor of the invasive mucinous carcinoma and has a potential for local recurrence. We report a series of 10 biopsy-proven EMPSGCs with their immunohistochemical features and review the literature.
汗腺肿瘤是罕见的附属器肿瘤，对眼科医生和病理学家来说都是一个诊断挑战。分泌性黏液汗腺癌（EMPSGC）是一种这样的肿瘤，被认为类似于实体乳头状乳腺癌。它通常影响老年人，在女性中更为常见，并且偏爱眼睑皮肤。尽管它具有惰性的临床过程，但 EMPSGC 被认为是侵袭性黏液癌的前体，并具有局部复发的潜力。我们报告了一系列经活检证实的 EMPSGC 的病例及其免疫组织化学特征，并回顾了文献。
