Hansen Stig Eiberg, Hasselstrøm Henriette, Grønfeldt Vivian, Froberg Karsten, Andersen Lars Bo
Institute of Exercise and Sport Sciences, University of Copenhagen, Copenhagen, Denmark.
Prev Med. 2005 Jun;40(6):740-6. doi: 10.1016/j.ypmed.2004.09.017.
To describe population values in cardiovascular disease (CVD) risk factors such as blood lipids, fasting insulin and glucose and blood pressure in this young age group, and calculate associations to fitness and fatness.
Participants were 369 boys (6.8 +/- 0.4 years) and 327 girls (6.7 +/- 0.4 years) from preschool classes in Copenhagen. Peak VO2, blood pressure (BP), fat content and anthropometry were determined. A fasting blood sample was analysed for insulin, glucose and blood lipids. Physical activity was measured using accelerometry.
Mean BMI, BP and blood lipids were not different between sexes. Fat percentage assessed from skinfolds was higher (21.5% vs. 16.5%) in girls than in boys (P < 0.001). Peak VO2 and physical activity were higher in boys than in girls (8% and 9%, respectively). Peak VO2 associated to fatness independent of body weight (r = 0.41; P < 0.001). Among the CVD risk factors, fitness was associated to high-density lipoprotein (HDL) (r = 0.14; P < 0.01) and physical activity (r = 0.12; P < 0.01). Fatness assessed by skinfold was associated to blood pressure (r = 0.19-0.28; P < 0.001), to fasting glucose (r = 0.11, P < 0.05) and insulin (r = 0.17; P < 0.001).
Mean BP in 6-7-year-old Danish children has decreased since 1979 and BMI has increased modestly since 1986/1987. The lipid profile was similar compared with data from 1973 and 1978 in Danish children. Weak relationships were found between CVD risk factors, fitness and fatness.
描述该年轻人群中心血管疾病（CVD）风险因素（如血脂、空腹胰岛素、血糖和血压）的人群数据，并计算其与健康状况和肥胖程度的关联。
研究对象为来自哥本哈根学前班的369名男孩（6.8±0.4岁）和327名女孩（6.7±0.4岁）。测定了峰值摄氧量、血压（BP）、脂肪含量和人体测量数据。采集空腹血样分析胰岛素、葡萄糖和血脂。使用加速度计测量身体活动情况。
男女之间的平均体重指数、血压和血脂无差异。通过皮褶厚度评估的女孩脂肪百分比（21.5%）高于男孩（16.5%）（P<0.001）。男孩的峰值摄氧量和身体活动高于女孩（分别高出8%和9%）。峰值摄氧量与肥胖程度相关，且不受体重影响（r=0.41；P<0.001）。在心血管疾病风险因素中，健康状况与高密度脂蛋白（HDL）相关（r=0.14；P<0.01）以及与身体活动相关（r=0.12；P<0.01）。通过皮褶厚度评估的肥胖程度与血压相关（r=0.19 - 0.28；P<0.001），与空腹血糖相关（r=0.11，P<0.05）以及与胰岛素相关（r=0.17；P<0.001）。
自1979年以来，丹麦6至7岁儿童的平均血压有所下降，自1986/1987年以来体重指数略有上升。与1973年和1978年丹麦儿童的数据相比，血脂谱相似。在心血管疾病风险因素、健康状况和肥胖程度之间发现了较弱的关联。
