Eisenmann J C, Katzmarzyk P T, Perusse L, Tremblay A, Després J-P, Bouchard C
Department of Health and Human Performance, Iowa State University, Ames, IA 50010, USA.
Int J Obes (Lond). 2005 Sep;29(9):1077-83. doi: 10.1038/sj.ijo.0802995.
The purpose of this study was to examine the association of body mass index (BMI) and aerobic fitness on cardiovascular disease (CVD) risk factors in adolescents.
The sample included 416 boys and 345 girls 9-18 y of age from the Québec Family Study. Participants were cross-tabulated into four groups using a median split of age-adjusted physical working capacity (PWC) and body mass index (BMI). Group differences in age-adjusted CVD risk factors (blood pressures, fasting total cholesterol (CHOL), LDL -C, HDL-C, HDL/CHOL, triglycerides, glucose, and a composite risk factor score) were examined by two-way ANOVA.
Several CVD risk factors showed significant main effects for PWC, BMI and/or the PWC by BMI interaction. In general, low fit males and females had higher blood lipids and glucose compared to their high fit counterparts within BMI categories although none of the differences reached statistical significance. The high fit/low BMI group showed the best CVD risk factor profile while the low fit/high BMI showed a poorer profile as evidenced by several significant differences between these two groups. Other significant differences occurred for various risk factors between groups.
Both aerobic fitness and BMI show an independent association with CVD risk factors in adolescents.
本研究旨在探讨青少年的体重指数（BMI）和有氧适能与心血管疾病（CVD）危险因素之间的关联。
样本包括来自魁北克家庭研究的416名9至18岁的男孩和345名女孩。参与者根据年龄调整后的身体工作能力（PWC）和体重指数（BMI）的中位数划分，交叉分为四组。通过双向方差分析检验年龄调整后的心血管疾病危险因素（血压、空腹总胆固醇（CHOL）、低密度脂蛋白胆固醇（LDL-C）、高密度脂蛋白胆固醇（HDL-C）、HDL/CHOL、甘油三酯、血糖和综合危险因素评分）的组间差异。
几个心血管疾病危险因素显示出PWC、BMI和/或PWC与BMI交互作用的显著主效应。总体而言，在BMI类别中，低适能的男性和女性与高适能的同龄人相比，血脂和血糖水平更高，尽管这些差异均未达到统计学显著性。高适能/低BMI组显示出最佳的心血管疾病危险因素概况，而低适能/高BMI组则显示出较差的概况，这两组之间的几个显著差异证明了这一点。各组之间的各种危险因素也存在其他显著差异。
有氧适能和BMI均与青少年心血管疾病危险因素存在独立关联。
