Rinne Teemu, Pekkola Johanna, Degerman Alexander, Autti Taina, Jääskeläinen Iiro P, Sams Mikko, Alho Kimmo
Department of Psychology, University of Helsinki, Finland.
Hum Brain Mapp. 2005 Oct;26(2):94-9. doi: 10.1002/hbm.20123.
We studied the effects of sound presentation rate and attention on auditory supratemporal cortex (STC) activation in 12 healthy adults using functional magnetic resonance imaging (fMRI) at 3 T. The sounds (200 ms in duration) were presented at steady rates of 0.5, 1, 1.5, 2.5, or 4 Hz while subjects either had to focus their attention to the sounds or ignore the sounds and attend to visual stimuli presented with a mean rate of 1 Hz. Consistent with previous observations, we found that both increase in stimulation rate and attention to sounds enhanced activity in STC bilaterally. Further, we observed larger attention effects with higher stimulation rates. This interaction of attention and presentation rate has not been reported previously. In conclusion, our results show both rate-dependent and attention-related modulations of STC indicating that both factors should be controlled, or at least addressed, in fMRI studies of auditory processing.
我们使用3T功能磁共振成像（fMRI）研究了声音呈现速率和注意力对12名健康成年人听觉颞上回（STC）激活的影响。持续时间为200毫秒的声音以0.5、1、1.5、2.5或4赫兹的稳定速率呈现，同时受试者要么必须将注意力集中在声音上，要么忽略声音并关注以1赫兹的平均速率呈现的视觉刺激。与之前的观察结果一致，我们发现刺激速率的增加和对声音的注意力都增强了双侧STC的活动。此外，我们观察到在较高刺激速率下注意力效应更大。注意力和呈现速率的这种相互作用此前尚未见报道。总之，我们的结果显示了STC的速率依赖性和注意力相关调制，表明在听觉处理的fMRI研究中，这两个因素都应得到控制，或至少加以考虑。
