Department of Ophthalmology, Taipei Veterans General Hospital, Taipei 11217, Taiwan.
Lupus. 2010 Feb;19(2):206-9. doi: 10.1177/0961203309345751. Epub 2009 Oct 30.
Combined central retinal artery occlusion and central retinal venous occlusion have been rarely reported in patients with systemic lupus erythematosus and anti-phospholipid syndrome. The impact of this severe vaso-occlusive disease on vision is usually devastating and permanent in spite of vigorous treatment. We report herein a 35-year-old female patient displaying a transient and reversible process. Her best-corrected visual acuity improved from 6/60 to 6/8.6 1 day later, before the initiation of systemic corticosteroid and anticoagulant treatment. The retina regained a normal appearance with her vision recovering to 6/6 2 weeks after the episode of temporary vision loss. Her rapid recovery suggests that continued anti-coagulation therapy and close follow-up to prevent severe complications and recurrent thrombosis is warranted.
合并性视网膜中央动脉阻塞和视网膜中央静脉阻塞在系统性红斑狼疮和抗磷脂综合征患者中很少见报道。尽管进行了积极的治疗,这种严重的血管阻塞性疾病对视功能的影响通常是毁灭性的和永久性的。我们在此报告一例 35 岁女性患者,其表现为短暂和可逆的过程。她的最佳矫正视力在 1 天后从 6/60 提高到 6/8.6,在开始全身皮质类固醇和抗凝治疗之前。在短暂视力丧失发作后 2 周,视网膜恢复正常外观,视力恢复至 6/6。她的快速恢复表明,需要继续抗凝治疗和密切随访,以预防严重并发症和复发性血栓形成。