Semple John L, Woolridge Nicholis, Lumsden Charles J
Division of Plastic Surgery, Department of Surgery, University of Toronto, Ontario, Canada.
Tissue Eng. 2005 Mar-Apr;11(3-4):341-56. doi: 10.1089/ten.2005.11.341.
The emergence of computational systems in tissue engineering and regenerative medicine is paralleling the rapid rise of new technology. Developments in software and hardware have allowed access to the huge data streams that are now available. The Human Genome Project led the way and opened many avenues for other branches of science and biology with extensive but contained databanks. The availability of vast amounts of data means nothing without the ability to integrate the information into a useful form. Tissue engineering has always been a practical science in which function and utility are key objectives. This review delineates key areas of this rapidly ascending branch of science and illustrates examples central to the successful integration of computational methods.
组织工程与再生医学中计算系统的出现与新技术的迅速崛起同步。软硬件的发展使得获取现有的海量数据流成为可能。人类基因组计划引领了这一潮流，并通过广泛但有限的数据库为科学和生物学的其他分支开辟了许多途径。如果没有将信息整合为有用形式的能力，大量数据的可用性就毫无意义。组织工程一直是一门实用科学，其中功能和实用性是关键目标。本综述阐述了这一迅速崛起的科学分支的关键领域，并举例说明了计算方法成功整合的核心实例。
