Hornig Ralf, Laube Thomas, Walter Peter, Velikay-Parel Michaela, Bornfeld Norbert, Feucht Matthias, Akguel Harun, Rössler Gernot, Alteheld Nils, Lütke Notarp Dietmar, Wyatt John, Richard Gisbert
IIP Technologies GmbH, Bonn, Germany.
J Neural Eng. 2005 Mar;2(1):S129-34. doi: 10.1088/1741-2560/2/1/014. Epub 2005 Feb 22.
This paper reports on methods and technical equipment to investigate the epiretinal stimulation of the retina in blind human subjects in acute trials. Current is applied to the retina through a thin, flexible microcontact film (microelectrode array) with electrode diameters ranging from 50 to 360 microm. The film is mounted in a custom-designed surgical tool that is hand-held by the surgeon during stimulation. The eventual goal of the work is the development of a chronically implantable retinal prosthesis to restore a useful level of vision to patients who are blind with outer retinal degenerations, specifically retinitis pigmentosa and macular degeneration.
本文报道了在急性试验中对盲人受试者视网膜进行视网膜前刺激的方法和技术设备。电流通过一种薄的、柔性微接触膜（微电极阵列）施加到视网膜上，电极直径范围为50至360微米。该膜安装在一个定制设计的手术工具中，在刺激过程中由外科医生手持。这项工作的最终目标是开发一种可长期植入的视网膜假体，为患有外层视网膜变性，特别是色素性视网膜炎和黄斑变性的盲人患者恢复有用的视力水平。
