生长激素与心血管功能。
Growth hormone and the cardiovascular function.
作者信息
Svensson J, Tivesten A, Isgaard J
机构信息
Research Centre for Endocrinology and Metabolism, Department of Internal Medicine, Sahlgrenska Academy, University of Göteborg, Göteborg, Sweden.
出版信息
Minerva Endocrinol. 2005 Mar;30(1):1-13.
In this review, the great importance of growth hormone (GH) for the maintenance of cardiac function in adult life is discussed. Physiological effects of GH are discussed as well as the cardiac dysfunction caused both by GH excess (acromegaly) and by GH deficiency in adult hypopituitary patients. In both acromegaly and adult GH deficiency, there is also increased cardiovascular morbidity and mortality. Finally, the effect of GH treatment in heart failure is discussed.
在这篇综述中，讨论了生长激素（GH）对成年期心脏功能维持的重要意义。文中探讨了GH的生理作用，以及成年垂体功能减退患者中GH分泌过多（肢端肥大症）和GH缺乏所导致的心脏功能障碍。在肢端肥大症和成年期GH缺乏这两种情况中，心血管疾病的发病率和死亡率也均有所增加。最后，还讨论了GH治疗对心力衰竭的影响。
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