Penderis J, Schwarz T, McConnell J F, Garosi L S, Thomson C E, Dennis R
Animal Health Trust, Lanwades Park, Kentford, Newmarket CB8 7UU.
Vet Rec. 2005 May 7;156(19):601-5. doi: 10.1136/vr.156.19.601.
Congenital anomalies of the vertebral column associated with aberrations of one of the primary vertebral ossification centres have been frequently described in the veterinary literature, but clinically significant abnormalities of secondary vertebral ossification centres, particularly involving the caudal articular processes, are much less frequently reported. This paper describes three dogs with aplasia and one dog with hypoplasia of the caudal vertebral articular processes. Thoracolumbar spinal cord compression and ataxia was evident in the three dogs with aplasia but no clinical signs were evident in the dog with hypoplasia. The radiographic appearance was similar in all four cases, with aplasia or hypoplasia of the caudal articular facets at one or more intervertebral joints in the thoracolumbar region. Bone proliferation was evident secondary to an associated degenerative joint disease. Compensatory hyperplasia of the adjacent cranial articular facets and ligamentum flavum protruded into the vertebral canal, resulting in a compressive myelopathy observed by myelography and magnetic resonance imaging.
与一个主要椎体骨化中心畸变相关的先天性脊柱异常在兽医文献中已有频繁描述，但继发性椎体骨化中心的临床显著异常，特别是涉及尾椎关节突的情况，报道则少得多。本文描述了三只尾椎关节突发育不全的犬和一只尾椎关节突发育不良的犬。三只发育不全的犬出现胸腰椎脊髓压迫和共济失调，但发育不良的犬未出现明显临床症状。所有四例的放射影像学表现相似，胸腰椎区域一个或多个椎间关节的尾椎关节面发育不全或发育不良。继发于相关退行性关节病的骨增生明显。相邻头侧关节突和黄韧带的代偿性增生突入椎管，导致脊髓造影和磁共振成像观察到压迫性脊髓病。
