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有癌症家族史的患者:识别与管理。

Patients with a family history of cancer: identification and management.

作者信息

Eberl Margaret M, Sunga Annette Y, Farrell Carolyn D, Mahoney Martin C

机构信息

Division of Cancer Prevention and Population Sciences, Roswell Park Cancer Institute, Buffalo, New York 14263, USA.

出版信息

J Am Board Fam Pract. 2005 May-Jun;18(3):211-7. doi: 10.3122/jabfm.18.3.211.

Abstract

A family history of certain malignancies, especially breast, ovarian, colorectal, and prostate cancers, can place persons at increased risk of developing these cancers. By constructing a pedigree that includes 3 generations, family physicians can identify patients at increased risk because of family cancer history. Persons at increased cancer risk because of family history warrant a surveillance strategy for early detection. Genetic professionals represent an important resource in assessing genetic risk and possible testing. Persons identified as being at increased risk of various cancers based on their family history should understand the surveillance plan that is recommended and the importance of maintaining a healthy lifestyle and remaining up to date on other cancer screening tests.

摘要

某些恶性肿瘤的家族史,尤其是乳腺癌、卵巢癌、结直肠癌和前列腺癌,会使人们患这些癌症的风险增加。通过构建包含三代人的家谱,家庭医生可以识别出因家族癌症史而风险增加的患者。因家族史而癌症风险增加的人需要一种早期检测的监测策略。遗传学专业人员是评估遗传风险和可能进行检测的重要资源。根据家族史被确定为患各种癌症风险增加的人应该了解推荐的监测计划,以及保持健康生活方式和及时进行其他癌症筛查检测的重要性。

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