迟发性精神分裂症样精神病患者：一项随访研究。
Patients with very-late-onset schizophrenia-like psychosis: a follow-up study.
作者信息
Mazeh Doron, Zemishlani Channa, Aizenberg Dov, Barak Yoram
机构信息
Psychogeriatric Dept., Abarbanel Mental Health Center, 15 KKL Street, Bat-Yam, 59100, Israel.
出版信息
Am J Geriatr Psychiatry. 2005 May;13(5):417-9. doi: 10.1176/appi.ajgp.13.5.417.
OBJECTIVE
The topic of course and outcome of very-late-onset schizophrenia-like psychosis (VLOSLP) has not received the research attention it deserves. The aim of this study was to evaluate the course of clinical symptoms and functional status of patients with VLOSLP in comparison with patients with life-long schizophrenia.
METHODS
Telephone interviews were conducted on primary caregivers of 21 patients with VLOSLP who had recently been released from inpatient care. Their treating staff evaluated 21 schizophrenia inpatients according to the same criteria.
RESULTS
The majority of patients with VLOSLP did not present cognitive and functional deterioration. On the other hand, 8 of the 19 patients in the elderly schizophrenia group had some functional decline; 3 of those 8 patients seemed to have some cognitive decline, as well.
CONCLUSIONS
The results suggest that the VLOSLP patients present stable cognitive and everyday functioning, as compared with chronically institutionalized elderly patients with schizophrenia.
目的
迟发性精神分裂症样精神病（VLOSLP）的病程及转归这一主题尚未得到应有的研究关注。本研究旨在评估VLOSLP患者的临床症状病程及功能状态，并与终生患精神分裂症的患者进行比较。
方法
对21例近期出院的VLOSLP患者的主要照料者进行电话访谈。其治疗团队根据相同标准对21例住院精神分裂症患者进行评估。
结果
大多数VLOSLP患者未出现认知和功能衰退。另一方面，老年精神分裂症组的19例患者中有8例出现了一定程度的功能下降；这8例患者中的3例似乎也有一定程度的认知下降。
结论
结果表明，与长期住院的老年精神分裂症患者相比，VLOSLP患者的认知和日常功能较为稳定。
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