臭矢茉莉的光保护活性。

Photoprotective activity of Buddleja scordioides.

作者信息

Avila Acevedo J G, Castañeda C M C, Benitez F J C, Durán D A, Barroso V R, Martínez C G, Muñoz L J L, Martínez C A, Romo de Vivar A

机构信息

Laboratorio de Fitoquímica, Unidad de Biología, Tecnología y Prototipos (UBIPRO), Universidad Nacional Autónoma de México, FES Iztacala, Tlalnepantla, C. P. 54090, México.

出版信息

Fitoterapia. 2005 Jun;76(3-4):301-9. doi: 10.1016/j.fitote.2005.03.009.

DOI:10.1016/j.fitote.2005.03.009

PMID:15890460

Abstract

The purpose of this study was to determine the photoprotective properties of the methanolic extract of Buddleja scordioides, as well as verbascoside and linarin which were isolated from this extract, and linarin acetate prepared in the laboratory. The photoprotective effect of substances against UV-B induced cellular death was evaluated by challenge experiments using Escherichia coli. Verbascoside and linarin acetate showed the highest protection. The sun protection factor (SPF) of the methanolic extract, linarin, linarin acetate, and verbascoside was evaluated by guinea pig bioassays. Verbascoside showed the largest SPF measurement.

摘要

本研究的目的是确定醉鱼草甲醇提取物以及从该提取物中分离出的毛蕊花糖苷和蒙花苷，还有在实验室制备的醋酸蒙花苷的光保护特性。通过使用大肠杆菌进行挑战实验，评估了这些物质对紫外线B诱导的细胞死亡的光保护作用。毛蕊花糖苷和醋酸蒙花苷表现出最高的保护作用。通过豚鼠生物测定法评估了甲醇提取物、蒙花苷、醋酸蒙花苷和毛蕊花糖苷的防晒系数（SPF）。毛蕊花糖苷的SPF测量值最大。