Bodner D R, Leffler B, Frost F
Division of Urology, Case Western Reserve University School of Medicine, Cleveland, Ohio 44124.
Paraplegia. 1992 Feb;30(2):118-20. doi: 10.1038/sc.1992.38.
Fifty-eight spinal cord injured men entered our self injection program for restoration of erections since the program began in September 1985. Early complications included sustained erection (greater than 8 hours) in 4 patients on 6 occasions requiring aspiration of the corpora cavernosa and injection of a dilute epinephrine solution (1/100,000). Bruising at the site of injection was reported at least once by 10 patients. Blood draining from the urethra was noted in 3 patients when the urethra was inadvertently injected. Rigid erections were obtained in all but 5 patients that injected (90%). Late complications included penile plaque in 3 patients (15%). There were no abnormal liver function tests. Average time on the injection program was 2 years (range of 0.5 to 4.5 years). Thirty-one (53%) of the patients have dropped out of the program, most doing so prior to the first injection or during the titration period. The average frequency of injection was twice a month. Injection therapy remains an effective and relatively safe alternative for selective patients with spinal cord injury.
自1985年9月该项目启动以来，58名脊髓损伤男性进入了我们的自我注射恢复勃起项目。早期并发症包括4名患者6次出现持续性勃起（超过8小时），需要抽吸海绵体并注射稀释的肾上腺素溶液（1/100,000）。10名患者至少报告过一次注射部位出现瘀伤。3名患者在无意中注射到尿道时出现尿道溢血。除5名注射患者外，其余患者均获得了坚硬勃起（90%）。晚期并发症包括3名患者出现阴茎硬结（15%）。肝功能检查均无异常。注射项目的平均时间为2年（范围为0.5至4.5年）。31名（53%）患者退出了该项目，大多数是在首次注射前或滴定期退出。平均注射频率为每月两次。注射疗法仍然是脊髓损伤选择性患者的一种有效且相对安全的替代方法。
