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海绵体内注射罂粟碱治疗脊髓损伤患者的阳痿

Intracavernous papaverine for impotence in spinal cord injured patients.

作者信息

Kapoor V K, Chahal A S, Jyoti S P, Mundkur Y J, Kotwal S V, Mehta V K

机构信息

Spinal Cord Injury Centre, Military Hospital, Kirkee, Pune, India.

出版信息

Paraplegia. 1993 Oct;31(10):675-7. doi: 10.1038/sc.1993.108.

Abstract

The majority of the spinal cord injury patients in our centre are young healthy males aged between 20 and 40 years. Loss of erection and inability to have coitus and father children have been responsible for inadequate sociosexual rehabilitation. In 1985, under urologist supervision, intracavernosal papaverine injection treatment was started in 101 volunteers, 65 paraplegics and 36 tetraplegics. Satisfactory erection sufficient for coital penetration was possible in 98 patients. Three had prolonged erection lasting beyond 4 hours. Only one required irrigation of the corpus with saline to achieve detumscence. One patient developed cavernosal fibrosis necessitating discontinuing the injection. Administration was under medical supervision so that possible complications of priapism/systemic effects could be promptly managed.

摘要

我们中心的大多数脊髓损伤患者是年龄在20至40岁之间的年轻健康男性。勃起功能丧失、无法进行性交和生育导致了社会性功能康复不足。1985年,在泌尿科医生的监督下,对101名志愿者(65名截瘫患者和36名四肢瘫痪患者)开始了海绵体内注射罂粟碱治疗。98名患者能够实现足以进行性交插入的满意勃起。3名患者出现持续超过4小时的长时间勃起。只有1名患者需要用盐水冲洗海绵体以实现消肿。1名患者出现海绵体纤维化,需要停止注射。给药在医学监督下进行,以便能及时处理阴茎异常勃起/全身效应的可能并发症。

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