Lloyd L K, Richards J S
Urological Rehabilitation and Research Center, Spain Rehabilitation Center, University of Alabama, Birmingham 35294.
Paraplegia. 1989 Dec;27(6):457-64. doi: 10.1038/sc.1989.72.
Sexual dysfunction due to inadequate or poorly sustained erections is a common problem among patients with spinal cord injury (SCI). While penile prostheses have provided adequate treatment for many patients, the complication rate in spinal cord injured patients remains high and they have not received widespread acceptance among SCI patients or the physicians treating them. Recently, intracavernous injections of vasoactive medications have proved beneficial for treating patients with erectile dysfunction. In the current study, we evaluated 40 SCI patients and 116 patients with vascular based impotence who had been followed for a minimum of 1 month while utilising intracavernous injections of phentolamine and papaverine. SCI patients with neurogenic based erectile dysfunction are significantly different from vascular impaired patients. SCI patients are younger and have been impotent for a longer period of time when treatment is sought. Furthermore, the dose of medication required is significantly less for SCI patients. The time of erection is longer and the quality of erection is better in neurogenic based impotence. Results with this treatment in SCI appear to be quite good with short term followup and long term evaluation of this methodology in SCI appears warranted.
因勃起不足或维持不佳导致的性功能障碍是脊髓损伤（SCI）患者中的常见问题。虽然阴茎假体为许多患者提供了有效的治疗方法，但脊髓损伤患者的并发症发生率仍然很高，并且在脊髓损伤患者或治疗他们的医生中尚未得到广泛接受。最近，海绵体内注射血管活性药物已被证明对治疗勃起功能障碍患者有益。在本研究中，我们评估了40例脊髓损伤患者和116例血管性阳痿患者，这些患者在使用酚妥拉明和罂粟碱海绵体内注射时至少随访了1个月。基于神经源性勃起功能障碍的脊髓损伤患者与血管受损患者有显著差异。脊髓损伤患者更年轻，在寻求治疗时阳痿的时间更长。此外，脊髓损伤患者所需的药物剂量明显更少。基于神经源性阳痿的勃起时间更长，勃起质量更好。在脊髓损伤患者中，这种治疗方法的短期随访结果似乎相当不错，因此有必要对该方法在脊髓损伤患者中的长期效果进行评估。
