Mery Frederic, Kawecki Tadeusz J
Section of Ecology and Evolution, Department of Biology, University of Fribourg, Chemin du Musée 10, CH-1700 Fribourg, Switzerland.
Science. 2005 May 20;308(5725):1148. doi: 10.1126/science.1111331.
Two distinct forms of consolidated associative memory are known in Drosophila: long-term memory and so-called anesthesia-resistant memory. Long-term memory is more stable, but unlike anesthesia-resistant memory, its formation requires protein synthesis. We show that flies induced to form long-term memory become more susceptible to extreme stress (such as desiccation). In contrast, induction of anesthesia-resistant memory had no detectable effect on desiccation resistance. This finding may help to explain why evolution has maintained anesthesia-resistant memory as another form of consolidated memory, distinct from long-term memory.
长期记忆和所谓的抗麻醉记忆。长期记忆更稳定，但与抗麻醉记忆不同，其形成需要蛋白质合成。我们发现，被诱导形成长期记忆的果蝇对极端应激（如脱水）变得更敏感。相比之下，诱导抗麻醉记忆对脱水抗性没有可检测到的影响。这一发现可能有助于解释为什么进化将抗麻醉记忆作为另一种巩固记忆的形式保留下来，与长期记忆不同。
