Onbaşi Kevser, Sahin Idris, Onbaşi Okan, Ustün Yusuf, Koca Doğan
Department of Internal Medicine, Yüzüncü Yil University School of Medicine, Van, Turkey.
Clin Rheumatol. 2005 Aug;24(4):365-9. doi: 10.1007/s10067-004-1045-x. Epub 2005 May 20.
Raynaud's phenomenon (RP) is a vasospastic disease and is characterized by ischemia of the digits, nose, and ears. The vasospasm can be triggered by cold weather, cold water, or emotional stress and is followed by triphasic color changes. First white color (ischemia), then blue color (congestion and cyanosis), and finally red color change (reactive hyperemia) can be observed. The prevalence is reported to be between 0.5 and 20% in different studies and is dependent on genetic, occupational, and environmental factors. The purpose of our study was to determine the prevalence of RP in an eastern part of Turkey among healthy subjects. A total of 768 people were included in the study. This cross-sectional study was conducted between April 2003 and October 2003 at the University Hospital and at the State Hospital in Van, Turkey. The participants were interviewed and examined to diagnose RP and a questionnaire and color charts were used. Of these 768 patients, 25 women and 20 men were diagnosed to have RP. A female predominance (25/20) was observed. Their mean age was 24.78 +/- 5.71 years. The prevalence of RP was 5.9% in our study population.
雷诺现象（RP）是一种血管痉挛性疾病，其特征为手指、鼻子和耳朵缺血。血管痉挛可由寒冷天气、冷水或情绪应激引发，随后会出现三相颜色变化。首先可观察到白色（缺血），接着是蓝色（充血和发绀），最后是红色变化（反应性充血）。不同研究报告的患病率在0.5%至20%之间，且取决于遗传、职业和环境因素。我们研究的目的是确定土耳其东部健康人群中雷诺现象的患病率。共有768人纳入本研究。这项横断面研究于2003年4月至2003年10月在土耳其凡城的大学医院和州立医院进行。对参与者进行访谈和检查以诊断雷诺现象，并使用了问卷和色卡。在这768名患者中，诊断出25名女性和20名男性患有雷诺现象。观察到女性占优势（25/20）。他们的平均年龄为24.78 +/- 5.71岁。我们研究人群中雷诺现象的患病率为5.9%。
