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羊膜移植术重建眼表三例报告

Amniotic membrane transplantation for the reconstruction of the ocular surface in three cases.

作者信息

Barros Paulo S M, Safatle Angélica M V, Godoy Cíntia A, Souza Mirian S B, Barros Luiz F M, Brooks Dennis E

机构信息

Ophthalmology Section, School of Veterinary Medicine, University of São Paulo, São Paulo, Brazil.

出版信息

Vet Ophthalmol. 2005 May-Jun;8(3):189-92. doi: 10.1111/j.1463-5224.2005.00391.x.

Abstract

This paper describes the use of amniotic membrane in the reconstructive surgical repair of generalized keratomalacia, ankyloblepharon, and after fibrous histiocytoma removal in two dogs and a cat. Case 1 was an 11-year-old female Yorkshire terrier with severe bullous keratomalacia in the left eye (OS). A frozen canine amniotic membrane graft and a third eyelid flap were applied. At day 80 postoperatively, only a mild scar and corneal vascularization were present. Case 2 was a 4-year-old female Siamese cat with symblepharon of both eyes after rhinotracheitis. Resection of the conjunctiva and frozen canine amniotic membrane transplant were performed. One month later, there was a little corneal scarring and corneal vascularization. Case 3 was a 6-year-old female terrier with a scleral and corneal mass at the 11-12 o'clock position (OS). Resection of the mass and amniotic membrane transplantation were performed. The mass was a fibrous histiocytoma localized to the sclera and cornea. This eye healed with mild conjunctivalization and no pigmentation. Amniotic membrane transplantation can be used as a method of reconstruction of the ocular surface with good repair of the cornea and minimal scarring in small animals.

摘要

本文描述了羊膜在两只犬和一只猫的广泛性角膜软化症、睑球粘连重建手术修复以及纤维组织细胞瘤切除术后的应用。病例1是一只11岁雌性约克夏梗犬,左眼(OS)患有严重的大疱性角膜软化症。应用了冷冻犬羊膜移植片和第三眼睑瓣。术后80天时,仅存在轻度瘢痕和角膜血管化。病例2是一只4岁雌性暹罗猫,患鼻气管炎后双眼发生睑球粘连。进行了结膜切除和冷冻犬羊膜移植。1个月后,有轻微角膜瘢痕形成和角膜血管化。病例3是一只6岁雌性梗犬,在11至12点位(OS)有巩膜和角膜肿物。进行了肿物切除和羊膜移植。肿物为局限于巩膜和角膜的纤维组织细胞瘤。该眼愈合时伴有轻度结膜化且无色素沉着。羊膜移植可作为一种眼表重建方法,在小动物中能很好地修复角膜且瘢痕形成最小。

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