Solga Steven F, Horska Alena, Clark Jeanne M, Diehl Anna Mae
Division of Gastroenterology, Johns Hopkins University, Baltimore, MD 21205, USA.
Liver Int. 2005 Jun;25(3):490-500. doi: 10.1111/j.1478-3231.2005.01131.x.
Hepatic phosphorus magnetic resonance spectroscopy (31P MRS) offers the exciting potential of studying metabolic processes in the human liver in vivo. Many investigators have utilized 31P MRS to research a broad range of metabolic questions, and there is outstanding potential for this imaging modality in the future. However, at times it is difficult to appreciate this potential because most published series have been small, and comparisons between studies are difficult. Indeed, the published literature contains significant variation in data acquisition and data analysis techniques and, perhaps most importantly, the interpretation of the data itself. As MR technology continues to evolve and more studies are being performed, perhaps a greater consensus of study techniques and endpoints will emerge. This review summarizes the present literature on human hepatic 31P MRS.
肝脏磷磁共振波谱（31P MRS）为在体研究人体肝脏的代谢过程提供了令人兴奋的潜力。许多研究者已利用31P MRS研究了广泛的代谢问题，并且这种成像方式在未来具有巨大潜力。然而，有时难以认识到这种潜力，因为大多数已发表的系列研究规模较小，且研究之间的比较困难。实际上，已发表的文献在数据采集和数据分析技术方面存在显著差异，或许最重要的是，在数据本身的解释方面也存在差异。随着磁共振技术不断发展且进行的研究越来越多，或许在研究技术和终点方面会出现更大的共识。本综述总结了目前关于人体肝脏31P MRS的文献。
