Liang Yuxue, Jing Qing, Li Xin, Shi Lei, Ding Kuiling
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, PR China.
J Am Chem Soc. 2005 Jun 1;127(21):7694-5. doi: 10.1021/ja050737u.
Programmed assembly strategy has been first applied to the generation of self-supported Noyori-type catalysts for asymmetric hydrogenation of ketones by spontaneous heterocoordination of bridged diphosphine and diamine ligands with Ru(II) metallic ions. The immobilized catalyst demonstrates excellent enantioselectivity and activity in the heterogeneous catalysis of the hydrogenation of aromatic ketones and can be recovered and recycled at least seven times without obvious loss of selectivity and activity.
程序化组装策略首次应用于通过桥连二膦和二胺配体与Ru(II)金属离子的自发异配位作用生成用于酮不对称氢化的自支撑诺伊里型催化剂。该固定化催化剂在芳香酮氢化的多相催化中表现出优异的对映选择性和活性，并且可以回收和循环使用至少七次，而选择性和活性没有明显损失。
